{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:41:22Z","timestamp":1761896482458,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,4,2]],"date-time":"2017-04-02T00:00:00Z","timestamp":1491091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the inpatient management for patients with acute idiopathic facial palsy (<jats:styled-content style=\"fixed-case\">IFP<\/jats:styled-content>) in Thuringia, Germany.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Population\u2010based study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>All inpatients with <jats:styled-content style=\"fixed-case\">IFP<\/jats:styled-content> in all hospitals with departments of otolaryngology and neurology in 2012, in the German federal state, Thuringia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Patients\u2019 characteristics and treatment were compared between departments, and the probability of recovery was tested.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 291 patients were mainly treated in departments of otolaryngology (55%) and neurology (36%). Corticosteroid treatment was the predominant therapy (84.5%). The probability to receive a facial nerve grading (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>=12.939; 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>]=3.599 to 46.516), gustatory testing (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>=6.878; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>=1.064 to 44.474) and audiometry (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>=32.505; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>=1.485 to 711.257) was significantly higher in otolaryngology departments, but lower for cranial <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>=0.192; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>=0.061 to 0.602), cerebrospinal fluid examination (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>=0.024; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>=0.006 to 0.102). A total of 131 patients (45%) showed a recovery to House\u2010Brackmann grade\u2264<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>. A pathological stapedial reflex test (Hazard ratio [<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>]=0.416; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>=0.180 to 0.959) was the only independent diagnostic predictor of worse outcome. Prednisolone dose &gt;500\u00a0mg (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>=0.579; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.400 to 0.838) and no adjuvant physiotherapy (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>=0.568; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>=0.407 to 0.794) were treatment\u2010related predictors of worse outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Inpatient treatment of <jats:styled-content style=\"fixed-case\">IFP<\/jats:styled-content> seems to be highly variable in daily practice, partly depending on the treating discipline and despite the availability of evidence\u2010based guidelines. The population\u2010based recovery rate was worse than reported in clinical trials.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12862","type":"journal-article","created":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T16:01:12Z","timestamp":1489161672000},"page":"1267-1274","source":"Crossref","is-referenced-by-count":18,"title":["Inpatient treatment of patients with acute idiopathic peripheral facial palsy: A population\u2010based healthcare research study"],"prefix":"10.1111","volume":"42","author":[{"given":"K.","family":"Plumbaum","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Jena University Hospital Jena Germany"},{"name":"Facial Nerve Center Jena Jena University Hospital Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.F.","family":"Volk","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Jena University Hospital Jena Germany"},{"name":"Facial Nerve Center Jena Jena University Hospital Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Boeger","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Zentralklinikum Suhl Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Buentzel","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology S\u00fcdharz\u2010Krankenhaus gGmbH Nordhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Esser","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology HELIOS\u2010Klinikum Erfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Steinbrecher","sequence":"additional","affiliation":[{"name":"Department of Neurology HELIOS\u2010Klinikum Erfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Sophien\/Hufeland\u2010Klinikum Weimar Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Jecker","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Klinikum Bad Salzungen Bad Salzungen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology SRH Wald\u2010Klinikum Gera Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Radtke","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Ilm\u2010Kreis\u2010Kliniken Arnstadt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.W.","family":"Witte","sequence":"additional","affiliation":[{"name":"Department of Neurology Jena University Hospital Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9671-0784","authenticated-orcid":false,"given":"O.","family":"Guntinas\u2010Lichius","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Jena University Hospital Jena Germany"},{"name":"Facial Nerve Center Jena Jena University Hospital Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072006"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70221-7"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b3354"},{"key":"e_1_2_7_5_1","first-page":"CD001869","article-title":"Antiviral treatment for Bell's palsy (idiopathic facial paralysis)","volume":"11","author":"Gagyor I","year":"2015","journal-title":"Cochrane Database Syst 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