{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T11:09:25Z","timestamp":1759057765471,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,5,25]],"date-time":"2017-05-25T00:00:00Z","timestamp":1495670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008376","name":"Helsingin ja Uudenmaan Sairaanhoitopiiri","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the bacterial species and patient clinical features in peritonsillar abscesses between patients who had renewal (renewal group) and those who did not (recovery group).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective comparative aetiological study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A total of 180 adult peritonsillar abscess patients were prospectively enrolled and treated as outpatients with incision and drainage and oral antibiotics. Bacteria from the pus were evaluated with a microarray assay. All contact with the healthcare system and renewal of the symptoms were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Different bacterial species and patient clinical features between the renewal and recovery groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 180 enrolled patients, 18 experienced a renewal of symptoms. Bacteria from the <jats:italic>Streptococcus<\/jats:italic> a<jats:italic>nginosus<\/jats:italic> group were detected in the patient samples of the renewal group more often than in those of the recovery group (<jats:italic>P<\/jats:italic>=.002). No isolated <jats:italic>Streptococcus pyogenes<\/jats:italic> samples were reported in the renewal group, while in the recovery group it was reported on 24% of the patients (<jats:italic>P<\/jats:italic>=.014). In the renewal group, patients over age 40 experienced symptom renewal faster than the younger patients (<jats:italic>P<\/jats:italic>=.013) and were more likely to be male (<jats:italic>P<\/jats:italic>=.036).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Bacteria in the <jats:italic>Streptococcus anginosus<\/jats:italic> group appear to predict renewal of <jats:styled-content style=\"fixed-case\">PTA <\/jats:styled-content><jats:italic>symptoms<\/jats:italic>, while <jats:italic>Streptococcus pyogenes<\/jats:italic> was not found in our patients with symptom renewal. Certain subgroups of patients should be followed more closely.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12893","type":"journal-article","created":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T17:25:55Z","timestamp":1493745955000},"page":"1358-1362","source":"Crossref","is-referenced-by-count":5,"title":["Renewal of peritonsillar abscess: Impact of the bacterial species of the infection and clinical features of the patient\u2014A prospective comparative aetiological study"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9722-805X","authenticated-orcid":false,"given":"J.","family":"Wikst\u00e9n","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery Helsinki University Hospital Helsinki Finland"},{"name":"Faculty of Medicine University of Helsinki Helsinki 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