{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T12:36:45Z","timestamp":1774528605507,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T00:00:00Z","timestamp":1497312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Anthony Long and Bernice Bibby Trusts"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Direct comparison of different diseases allows clinicians and researchers to place the burden of symptoms and impact on quality of life of each condition in context. Generic health\u2010related quality\u2010of\u2010life assessment tools allow such analysis, and limited data are available for British patients with chronic rhinosinusitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>As part of a larger feasibility study, patients underwent baseline assessment using the <jats:styled-content style=\"fixed-case\">SNOT<\/jats:styled-content>\u201022, <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201012 and <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D\u20105L tools. Data were analysed using Microsoft Excel and algorithms available for the analysis of the later two tools. We plotted <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D\u20105L <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> and utility scores and <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201012 <jats:styled-content style=\"fixed-case\">MCS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> scores separately against <jats:styled-content style=\"fixed-case\">SNOT<\/jats:styled-content>\u201022 scores and quantified associations using bivariate ordinary least squares regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Patients were prospectively recruited from six <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> outpatient clinics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Adult patients with chronic rhinosinusitis without nasal polyps (<jats:styled-content style=\"fixed-case\">CRS<\/jats:styled-content>s<jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content>s).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome measures<\/jats:title><jats:p>Baseline <jats:styled-content style=\"fixed-case\">SNOT<\/jats:styled-content>\u201022, <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201012 and <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D\u20105L scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010two adults were recruited with a mean age of 55 years, 51% were male. The mean <jats:styled-content style=\"fixed-case\">SNOT<\/jats:styled-content>\u201022 score was 43.82. Mental and physical component scores of the <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201012 were 46.53 and 46, respectively. Mean index score computed form the <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D\u20105L was 0.75. Worse (higher) <jats:styled-content style=\"fixed-case\">SNOT<\/jats:styled-content>\u201022 scores were associated with lower <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D\u20105L <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> and utility scores and <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201012 <jats:styled-content style=\"fixed-case\">MCS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D\u20105L suggests that British <jats:styled-content style=\"fixed-case\">CRS<\/jats:styled-content>s<jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content>s patients are negatively impacted with regards to quality of life. We found the <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201012 to be less sensitive and conclude that the <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D\u20105L tool is a quick and accessible method for assessing <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> in order it can be compared with other disease states.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.12903","type":"journal-article","created":{"date-parts":[[2017,5,12]],"date-time":"2017-05-12T13:54:47Z","timestamp":1494597287000},"page":"90-95","source":"Crossref","is-referenced-by-count":8,"title":["Health utility reporting in chronic rhinosinusitis patients"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5424-3129","authenticated-orcid":false,"given":"J.","family":"Bewick","sequence":"first","affiliation":[{"name":"James Paget University Hospital Gorleston UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Morris","sequence":"additional","affiliation":[{"name":"University College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Guys &amp; St Thomas\u2019 Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Erskine","sequence":"additional","affiliation":[{"name":"Norwich Medical School University of East Anglia Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1125-3236","authenticated-orcid":false,"given":"C.M.","family":"Philpott","sequence":"additional","affiliation":[{"name":"James Paget University Hospital Gorleston UK"},{"name":"Norwich Medical School University of East Anglia Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-010-0175-2"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/00034894041130S502"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2009.01995.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0738-3991(93)90128-J"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-017-0233-1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-1-54"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199401000-00004"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12189"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25054"},{"key":"e_1_2_8_11_1","doi-asserted-by":"crossref","DOI":"10.4193\/Rhin16.111","article-title":"Chronic rhinosinusitis and mood disturbance","author":"Erskine S","year":"2017","journal-title":"Rhinology"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24135"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12685"},{"key":"e_1_2_8_15_1","first-page":"1","article-title":"European Position Paper on Rhinosinusitis and Nasal Polyps 2012","author":"Fokkens WJ","year":"2012","journal-title":"Rhinol Suppl"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12667"},{"key":"e_1_2_8_17_1","unstructured":"OemarM&JanssenB.EQ\u20105D\u20105L User Guide: EuroQoL Group.2013. 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