{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:34:04Z","timestamp":1761824044057,"version":"3.37.3"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T00:00:00Z","timestamp":1533600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Clinicians have recognised the role of narrow band imaging (<jats:styled-content style=\"fixed-case\">NBI<\/jats:styled-content>) in the management of head and neck cancer in several studies. However, a recent systematic review was unable to pool the data on diagnostic efficacy in this setting owing to the heterogeneity in the published data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Secondary analysis of data, utilising Bayes' theorem, from meta\u2010analyses and randomised trials.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In patients with a histological diagnosis of mild dysplasia who show no abnormalities on <jats:styled-content style=\"fixed-case\">NBI<\/jats:styled-content>, the post\u2010test probability of malignancy is estimated to be 2.3%, compared to 10.3% with conventional white light imaging (<jats:styled-content style=\"fixed-case\">WLI<\/jats:styled-content>). For severe dysplasia, similar post\u2010test probabilities after <jats:styled-content style=\"fixed-case\">NBI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">WLI<\/jats:styled-content> are estimated to be 8.0% and 29.7%, respectively. Post\u2010test probabilities in this setting indicate the chance of missing malignancy following a negative <jats:styled-content style=\"fixed-case\">NBI<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">WLI<\/jats:styled-content> in patients who undergo no further intervention. This study also provides a nomogram designed for use in this setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study identifies the evidence base for use of <jats:styled-content style=\"fixed-case\">NBI<\/jats:styled-content> in the follow\u2010up for laryngeal dysplasia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.13182","type":"journal-article","created":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T19:41:56Z","timestamp":1530733316000},"page":"1439-1442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Laryngeal dysplasia and narrow band imaging: Secondary analysis of published data supports the role in patient follow\u2010up"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7933-4585","authenticated-orcid":false,"given":"Vinidh","family":"Paleri","sequence":"first","affiliation":[{"name":"The Royal Marsden NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1249-731X","authenticated-orcid":false,"given":"Rupali","family":"Sawant","sequence":"additional","affiliation":[{"name":"Biostatistics Research Group Institute of Health &amp; Society Newcastle University Newcastle upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisham","family":"Mehanna","sequence":"additional","affiliation":[{"name":"St. John's Hospital Livingston UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holly","family":"Ainsworth","sequence":"additional","affiliation":[{"name":"Institute of Head and Neck Studies and Education University of Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Stocken","sequence":"additional","affiliation":[{"name":"Institute of Health &amp; Society Newcastle University Newcastle upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2009.01938.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2010.02119.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215115000833"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24300"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2010.02181.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.4680"},{"key":"e_1_2_8_8_1","first-page":"279","article-title":"Doc, what are my chances?","volume":"32","author":"Marasco J","year":"2011","journal-title":"UMAP J"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0962280215592907"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197507312930513"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/eb-2013-101243"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12728"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489414556082"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-4244-6"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215115002972"}],"container-title":["Clinical Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcoa.13182","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.13182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T08:36:27Z","timestamp":1694680587000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/coa.13182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,7]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1111\/coa.13182"],"URL":"https:\/\/doi.org\/10.1111\/coa.13182","archive":["Portico"],"relation":{},"ISSN":["1749-4478","1749-4486"],"issn-type":[{"type":"print","value":"1749-4478"},{"type":"electronic","value":"1749-4486"}],"subject":[],"published":{"date-parts":[[2018,8,7]]},"assertion":[{"value":"2017-07-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}