{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T17:50:56Z","timestamp":1770832256339,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T00:00:00Z","timestamp":1547424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006975","name":"Indiana Clinical and Translational Sciences Institute","doi-asserted-by":"publisher","award":["UL1 RR02578"],"award-info":[{"award-number":["UL1 RR02578"]}],"id":[{"id":"10.13039\/100006975","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To translate and validate the Zurich Chronic Middle Ear Inventory (ZCMEI\u201021) for the English language in order to provide an English instrument to assess health\u2010related quality of life in chronic otitis media (COM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Pilot translation study including cognitive debriefings, prospective multicentre cross\u2010sectional psychometric validation study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Four tertiary referral centres in three different English\u2010speaking countries (UK, USA and Australia).<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Adult patients suffering from COM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The English translation of the ZCMEI\u201021 (ZCMEI\u201021\u2010E) and the five\u2010level version of the EQ\u20105D questionnaire. The EQ\u20105D, which constitutes a generic measure of health\u2010related quality of life, consists of a descriptive system score and a visual analogue scale. Statistical outcomes included single\u2010item descriptive statistics, internal consistency (Cronbach's <jats:italic>\u03b1<\/jats:italic>) as an indicator of reliability, as well as construct validity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 124 patients suffering from COM were included. The mean age was 50.1\u00a0years (SD 16.9\u00a0years), and 72 (58.1%) were males. The Cronbach's <jats:italic>\u03b1<\/jats:italic> of the ZCMEI\u201021\u2010E was 0.91, suggesting an excellent internal consistency. The Spearman's correlation coefficient of the ZCMEI\u201021\u2010E total score was 0.55 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001) for convergent construct validity with EQ\u20105D descriptive system score and 0.57 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001) with the EQ\u20105D visual analogue scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The ZCMEI\u201021\u2010E is a new validated questionnaire that provides clinicians with a short, comprehensive and reliable instrument to quantify health\u2010related quality of life in patients suffering from COM. The ZCMEI\u201021\u2010E may be of use in clinical routine as well as in outcome research and monitoring.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.13275","type":"journal-article","created":{"date-parts":[[2018,12,27]],"date-time":"2018-12-27T06:15:06Z","timestamp":1545891306000},"page":"254-262","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["English translation and validation of the Zurich chronic middle ear inventory (ZCMEI\u201021\u2010E) assessing quality of life in chronic otitis media: A prospective international multicentre study"],"prefix":"10.1111","volume":"44","author":[{"given":"Michail","family":"Chatzimichalis","sequence":"first","affiliation":[{"name":"Dorset County Hospital Dorchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenz","family":"Epprecht","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery Massachusetts 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