{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T22:56:31Z","timestamp":1769122591518,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T00:00:00Z","timestamp":1577059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study assesses the ability to reconstruct costal cartilage images by using three\u2010dimensional visualisation software (Mimics) based on semi\u2010automated segmentation algorithm and to investigate its reliability and validity with an anthropometric analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Observational prospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Plastic surgery department of a tertiary hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Twenty\u2010two microtia patients who underwent autologous ear reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Preoperative thoracic computed tomography data were processed to Mimics software for three\u2010dimensional costal cartilage imaging. The length, width, thickness and volume of the 9th costal cartilages were calculated from these images and compared with the direct measurements (DM) obtained intraoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The intra\u2010examiner reliability and inter\u2010examiner reliability were high in terms of all four measurements (intraclass correlation coefficients, ICC: 0.876\u20100.984). There were no significant differences between image\u2010based anthropometry and DM in the linear measurements except for the volume (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05). The mean volume calculation error of Mimics was \u22120.08\u00a0\u00b1\u00a00.13\u00a0mL. No correlation was found between the anthropometric variables and the absolute errors (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a0.05). Furthermore, Bland\u2010Altman plots were used to evaluate the agreement between the two methods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite a very small error was found in volume calculation, Mimics software was accurate and reliable in linear calculation. Three\u2010dimensional costal cartilage imaging was found to be an efficient tool for morphological evaluation of costal cartilages. We believe that with the application of individualised cartilage models based on three\u2010dimensional printing, the use of customised ear framework carving will be practicable in surgical training.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.13491","type":"journal-article","created":{"date-parts":[[2019,12,7]],"date-time":"2019-12-07T07:52:38Z","timestamp":1575705158000},"page":"204-210","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Validity and reliability of three\u2010dimensional costal cartilage imaging for donor\u2010site assessment and clinical application in microtia reconstruction patients: A prospective study of 22 cases"],"prefix":"10.1111","volume":"45","author":[{"given":"Xiaoyan","family":"Mao","sequence":"first","affiliation":[{"name":"Department of Plastic and Aesthetic Surgery Nanfang Hospital Southern Medical University Guangzhou 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