{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T21:38:40Z","timestamp":1772487520241,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T00:00:00Z","timestamp":1611446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We assessed associations of potential factors with orbital complications in acute rhinosinusitis (ARS) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>An unmatched case\u2010control study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>A tertiary referral hospital in Thailand.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Consecutive outpatients of any age with severe ARS (visual analog scale\u00a0\u2265\u00a07) with and without orbital complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Patients were enrolled from January 2013 to December 2018. Forty\u2010three ARS patients (55.8% female, median age 45.6, (range 2.0\u201093.0) years) were included, with 19 patients in the complicated group and 24 in the uncomplicated group. Patient characteristics (gender, age, diabetes, immune status), symptoms and signs, site of infection and type of pathogenic bacteria were recorded and assessed their associations with orbital complications by univariable and multivariable logistic regression analyses. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The most common orbital complication was subperiosteal abscess (42.1%), followed by orbital cellulitis (15.8%) and cavernous sinus thrombosis (10.5%). Multivariable logistic regression analysis demonstrated a positive association with orbital complications (pseudo R<jats:sup>2<\/jats:sup> 0.4) for ethmoid sinusitis (OR 31.1, 95% CI [2.3\u2010430.6]) and a short duration of symptoms (OR 0.9, 95% CI [0.8\u20100.9]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Orbital complications were associated with ethmoid sinusitis with a short duration of ARS symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.13718","type":"journal-article","created":{"date-parts":[[2021,1,16]],"date-time":"2021-01-16T21:37:55Z","timestamp":1610833075000},"page":"587-593","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Risk factors of orbital complications in outpatients presenting with severe rhinosinusitis: A case\u2010control study"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7537-4718","authenticated-orcid":false,"given":"Kornkiat","family":"Snidvongs","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Endoscopic Nasal and Sinus Surgery Excellence Center King Chulalongkorn Memorial Hospital Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9787-6767","authenticated-orcid":false,"given":"Wirach","family":"Chitsuthipakorn","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Rajavithi Hospital Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chatdanai","family":"Akarapas","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Chulalongkorn University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songklot","family":"Aeumjaturapat","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Endoscopic Nasal and Sinus Surgery Excellence Center King Chulalongkorn Memorial Hospital Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supinda","family":"Chusakul","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Endoscopic Nasal and Sinus Surgery Excellence Center King Chulalongkorn Memorial Hospital Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesada","family":"Kanjanaumporn","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Endoscopic Nasal and Sinus Surgery Excellence Center King Chulalongkorn Memorial Hospital Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0158-7638","authenticated-orcid":false,"given":"Kachorn","family":"Seresirikachorn","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Endoscopic Nasal and Sinus Surgery Excellence Center King Chulalongkorn Memorial Hospital Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,24]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmr062"},{"key":"e_1_2_11_3_1","first-page":"59","article-title":"Intracranial complications of rhinosinusitis. A review, typical imaging data and algorithm of management","volume":"47","author":"Bayonne E","year":"2009","journal-title":"Rhinology"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197009000-00007"},{"key":"e_1_2_11_5_1","first-page":"1","article-title":"European position paper on rhinosinusitis and nasal polyps 2012","volume":"23","author":"Fokkens WJ","year":"2012","journal-title":"Rhinol Suppl"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3171\/2011.3.PEDS10504"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2013.04.031"},{"key":"e_1_2_11_8_1","first-page":"195","article-title":"Prospective study of 43 severe complications of acute rhinosinusitis","volume":"127","author":"Stoll D","year":"2006","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.04.027"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199103000-00003"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199707000-00005"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(92)90184-4"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240101500606"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino09.130"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199704000-00002"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016481003645727"}],"container-title":["Clinical Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.13718","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/coa.13718","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.13718","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T19:59:19Z","timestamp":1692820759000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/coa.13718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,24]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/coa.13718"],"URL":"https:\/\/doi.org\/10.1111\/coa.13718","archive":["Portico"],"relation":{},"ISSN":["1749-4478","1749-4486"],"issn-type":[{"value":"1749-4478","type":"print"},{"value":"1749-4486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,24]]},"assertion":[{"value":"2020-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}