{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:54:48Z","timestamp":1761648888021,"version":"3.40.5"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T00:00:00Z","timestamp":1622419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Although unilateral laryngeal immobility (ULI) can results from paralysis or ankylosis of the cricoarytenoid joint, no comparative study exists to date. Aim of this study was to compare clinical features, aetiologies, spontaneous recovery and evolution after surgical treatment of ULI according to its mechanism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Longitudinal observational cohort study between 1992 and 2017 in a tertiary care referral centre and university teaching hospital. All adult patients with isolated ULI were included. Presenting symptoms and demographic data were recorded at baseline. During follow\u2010up, natural recovery and, if a surgical treatment was performed, treatment failure rate were noted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>994 patients were included, 56.4% of male and with a mean age of 58 years. Overall, 91% had paralysis and 9% had ankylosis. Dysphonia was the main symptom in both groups (&gt;96%). Dyspnoea was more frequent in patients with ankylosis (26.1% vs 4.2% in those with paralysis) whereas dysphagia was more frequent in those with paralysis (31.1% vs 20% in those with ankylosis). With a mean follow\u2010up of 2.3 years (\u00b15.1), spontaneous recovery did not differ according to ULI\u2019s aetiology (hazard ratio 1.43, 95% confidence interval 0.85\u20102.40). Overall, 37.1% underwent a surgical treatment, and paralysis was associated with a lower odd of treatment failure (hazard ratio 0.27, 95% confidence interval 0.10\u20100.70) over a mean follow\u2010up of 3.1\u00a0years (\u00b14.1).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ULI resulting from paralysis or ankylosis differ in their symptoms and responses to surgical treatment, whereas natural evolution was similar.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.13792","type":"journal-article","created":{"date-parts":[[2021,5,2]],"date-time":"2021-05-02T02:05:12Z","timestamp":1619921112000},"page":"1057-1064","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Characteristics, natural evolution and surgical treatment outcomes of unilateral laryngeal paralysis versus ankylosis: A longitudinal cohort study"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4194-6145","authenticated-orcid":false,"given":"Quentin","family":"Lisan","sequence":"first","affiliation":[{"name":"Department of Integrative Epidemiology INSERM UMR 970 PARCC  Paris France"},{"name":"Department of Head and Neck Surgery Foch Hospital, School of Medicine, UFR Simone Veil Universite Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University)  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florent","family":"Couineau","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Ren\u00e9 Dubos Hospital  Pontoise France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ollivier","family":"Laccourreye","sequence":"additional","affiliation":[{"name":"Faculty of Health School of Medicine Universit\u00e9 de Paris  Paris France"},{"name":"Head and Neck Surgery AP\u2010HP.Centre\u2010Universit\u00e9 de Paris H\u00f4pital Europ\u00e9en Georges Pompidou  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40136-014-0043-z"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.5535\/arm.2017.41.6.1019"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2016.09.006"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24980"},{"issue":"6","key":"e_1_2_9_6_1","first-page":"420","article-title":"The diagnostic value of laryngeal electromyography in vocal fold paralysis and arytenoid dislocation","volume":"32","author":"Yu PC","year":"2018","journal-title":"Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2019.3072"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2004.11.002"},{"issue":"11","key":"e_1_2_9_9_1","first-page":"1045","article-title":"Clinical features and surgical outcomes following closed reduction of arytenoid dislocation. 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