{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T17:30:02Z","timestamp":1770139802704,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To explore the impact of COVID\u201019 on the management and outcomes of acute paediatric mastoiditis across the UK.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>National retrospective and prospective audit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>48 UK secondary care ENT departments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Consecutive children aged 18\u00a0years or under, referred to ENT with a clinical diagnosis of mastoiditis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Cases were divided into Period 1 (01\/11\/19\u201015\/03\/20), before the UK population were instructed to reduce social contact, and Period 2 (16\/03\/20\u201030\/04\/21), following this. Periods 1 and 2 were compared for population variables, management and outcomes. Secondary analyses compared outcomes by primary treatment (medical\/needle aspiration\/surgical).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>286 cases met criteria (median 4 per site, range 0\u201324). 9.4 cases were recorded per week in period 1 versus 2.0 in period 2, with no winter increase in cases in December 2020\u2010Febraury 2021. Patient age differed between periods 1 and 2 (3.2\u00a0vs 4.7\u00a0years respectively, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.001). 85% of children in period 2 were tested for COVID\u201019 with a single positive test. In period, 2 cases associated with <jats:italic>P.\u00a0aeruginosa<\/jats:italic> significantly increased. 48.6% of children were scanned in period 1 vs 41.1% in period 2. Surgical management was used more frequently in period 1 (43.0% vs 24.3%, <jats:italic>p\u00a0<\/jats:italic>=\u00a00.001). Treatment success was high, with failure of initial management in 6.3%, and 30\u2010day re\u2010admission for recurrence in 2.1%. The adverse event rate (15.7% overall) did not vary by treatment modality or between periods 1&amp; 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The COVID\u201019 pandemic led to a significant change in the presentation and case mix of acute paediatric mastoiditis in the UK.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.13869","type":"journal-article","created":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T01:57:18Z","timestamp":1633485438000},"page":"120-130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Acute paediatric mastoiditis in the UK before and during the COVID\u201019 pandemic: A national observational study"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8147-1549","authenticated-orcid":false,"given":"Matthew E.","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Salford Royal Hospital Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Huw","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Gloucestershire Hospitals NHS Foundation Trust Gloucester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6591-5119","authenticated-orcid":false,"given":"John C.","family":"Hardman","sequence":"additional","affiliation":[{"name":"The Head and Neck Unit The Royal Marsden Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaya","family":"Nichani","sequence":"additional","affiliation":[{"name":"Paediatric Otolaryngology Department Royal Manchester Children's Hospital University of Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadie","family":"Khwaja","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Manchester University Foundation Trust Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The INTEGRATE (The UK ENT Trainee Research Network) UK Acute Paediatric Mastoiditis Audit Collaborators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iain A.","family":"Bruce","sequence":"additional","affiliation":[{"name":"Paediatric ENT Department, Royal Manchester Children's Hospital, MAHSC University of Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Rea","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Leicester Royal Infirmary Leicester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.09.032"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.07.014"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2020.1922"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2021.110714"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13049\u2010020\u201000810\u20100"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431\u2010020\u201003747\u20109"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10020196"},{"key":"e_1_2_9_9_1","unstructured":"ENTUK (The professional membership body for Ear Nose and Throat surgery and related specialties in the UK).https:\/\/www.entuk.org\/guidance\u2010undertaking\u2010otological\u2010procedures\u2010during\u2010covid\u201019\u2010pandemic\u20100. 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