{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T01:34:47Z","timestamp":1783128887709,"version":"3.54.6"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,4]],"date-time":"2021-11-04T00:00:00Z","timestamp":1635984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["2020R1F1A1072209"],"award-info":[{"award-number":["2020R1F1A1072209"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The present meta\u2010analysis sought to assess further evidence for the efficacy of steroids in vestibular neuritis (VN).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The PubMed, EMBASE and Cochrane Library databases were searched through 30 August 2019. The main outcome measure was dizziness handicap inventory (DHI) and secondary outcomes included complete caloric recovery and improvement of canal paresis (CP). The follow\u2010up times were divided into short, mid and long\u2010term.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 276 records identified, 5\u00a0studies (<jats:italic>n<\/jats:italic>\u00a0=\u00a0253) were included in the analysis. The therapeutic effect of steroid on VN was confirmed (Hedges\u2019 g\u00a0=\u00a00.172, 95% CI 0.05\u20130.30, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.006). Although there was no significant difference between steroids and control in the DHI score (Hedges\u2019 g\u00a0=\u00a0\u22120.323, 95% CI \u22120.533 to \u22120.113, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.01), significant effect was seen on complete caloric recovery and improvement in CP (Hedges\u2019 g\u00a0=\u00a00.364, 95% CI 0.18\u20130.55, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.0001; Hedges\u2019 g\u00a0=\u00a00.592, 95% CI 0.32\u20130.59, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results suggest that corticosteroids have an effect on the results of caloric tests for VN recovery, especially in long\u2010term follow\u2010up. However, in terms of dizziness handicap, we did not find any evidence of positive effect on corticosteroid. More data are required before recommendations can be made regarding management in patients on corticosteroids.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.13880","type":"journal-article","created":{"date-parts":[[2021,10,23]],"date-time":"2021-10-23T01:15:01Z","timestamp":1634951701000},"page":"34-43","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Therapeutic effect of steroids on vestibular neuritis: Systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1914-8331","authenticated-orcid":false,"given":"Gaeun","family":"Kim","sequence":"first","affiliation":[{"name":"The Research Institute for Nursing Science College of Nursing Keimyung University Daegu Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8443-8581","authenticated-orcid":false,"given":"Jae\u2010Hyun","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery College of Medicine The Catholic University of Korea Seoul Korea"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Seoul St. Mary\u2019s hospital Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Jae","family":"Lee","sequence":"additional","affiliation":[{"name":"Medical Library The Catholic University of Korea Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0401-1183","authenticated-orcid":false,"given":"Dong\u2010Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery College of Medicine The Catholic University of Korea Seoul Korea"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Uijeongbu St Mary's Hospital Uijeongbu City Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,4]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-85729-591-0"},{"key":"e_1_2_12_3_1","volume-title":"Cummings Otolaryngology\u2010Head and Neck Surgery","author":"Crane BT","year":"2015"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1354598"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1179\/016164103101201364"},{"issue":"5","key":"e_1_2_12_6_1","first-page":"CD008607","article-title":"Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis)","volume":"11","author":"Fishman JM","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES-180645"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002106"},{"key":"e_1_2_12_9_1","unstructured":"DeeksJJ HigginsJ AltmanDG GreenS. 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