{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T05:11:06Z","timestamp":1784005866221,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T00:00:00Z","timestamp":1649116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Locally aggressive thyroid cancer can result in airway obstruction secondary to tracheal compression or vocal cord palsy. A tracheal stent provides an alternative to surgical resection, tracheostomy or conservative management in patients with compressive symptoms. This systematic review synthesises the current evidence associated with tracheal stenting in locally advanced thyroid cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design, setting and participants<\/jats:title><jats:p>We conducted a systematic review of tracheal stenting in locally advanced thyroid cancers. We searched MEDLINE, Embase and Web of Science for studies until 22 September 2020. Inclusion criteria were studies involving patients who had received tracheal stents to treat laryngotracheal stenosis secondary to locally advanced thyroid cancer. Single case reports or single cases were not included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>We assessed studies for data on the performance of tracheal stenting; defined as symptomatic relief, spirometry data, complication rates and mortality. We also extracted data pertaining to the use of different types of stent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified eight full\u2010text articles from 325 titles found in our search. These were all single\u2010centre retrospective studies that lacked homogeneity of thyroid cancer histotypes. The number of patients in each study ranged from 4 to 35 patients. Stenting improved performance status (two of two studies), symptoms (five of five studies) and spirometry (two of three studies). The most common complications were tracheal granulation, tumour overgrowth, stent migration and sputum retention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is a lack of evidence in the literature of tracheal stents in locally advanced thyroid cancer. However, the evidence available suggests tracheal stenting may be a useful treatment adjunct in advanced thyroid cancer\u2010causing symptomatic airway obstruction.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.13923","type":"journal-article","created":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T20:13:41Z","timestamp":1645906421000},"page":"414-423","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A systematic review of endotracheal stenting in patients with locally advanced thyroid cancer"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8530-1643","authenticated-orcid":false,"given":"James","family":"Schuster\u2010Bruce","sequence":"first","affiliation":[{"name":"Department of Ear, Nose and Throat, Head and Neck Surgery St George\u2019s University Hospitals NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pippa","family":"Sargent","sequence":"additional","affiliation":[{"name":"Department of Medicine St George\u2019s University Hospitals NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Madden","sequence":"additional","affiliation":[{"name":"Department of Medicine St George\u2019s University Hospitals NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enyinnaya","family":"Ofo","sequence":"additional","affiliation":[{"name":"Department of Ear, Nose and Throat, Head and Neck Surgery St George\u2019s University Hospitals NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Allin","sequence":"additional","affiliation":[{"name":"Department of Ear, Nose and Throat, Head and Neck Surgery Imperial College NHS Healthcare Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,5]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.84.11.6115"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-013-2173-8"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215115001103"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000037"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(78)90042-9"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e3181726d36"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2010.03.013"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0302"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-017-0439-7"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116000359"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116000578"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23857"},{"issue":"2","key":"e_1_2_13_14_1","first-page":"72","article-title":"Problems of tracheotomy in locally invasive anaplastic thyroid cancer","volume":"374","author":"H\u00f6lting T","year":"1989","journal-title":"Langenbecks Arch Chir"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2008.01309.x"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.2.723"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2014.350"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841851.2010.491093"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03344085"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-2963-0"},{"key":"e_1_2_13_21_1","volume-title":"StatPearls","author":"Sanivarapu RR","year":"2021"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2535"},{"key":"e_1_2_13_23_1","unstructured":"Cochrane.Assessing risk of bias in included studies[Internet]. Available from:https:\/\/methods.cochrane.org\/bias\/sites\/methods.cochrane.org.bias\/files\/public\/uploads\/6.%20Assessing%20risk%20of%20bias%20in%20included%20studies%20v1.0%20Standard%20author%20slides.pdf"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-003-2022-5"},{"key":"e_1_2_13_25_1","unstructured":"Boston Scientific.UltraflexTM Tracheobronchial stent system[Internet]. Available from:https:\/\/www.bostonscientific.com\/en\u2010US\/products\/stents\u2010\u2010pulmonary\/Ultraflex_Tracheobronchial_Stent.html"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(97)70040-0"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.4749.65"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-198212000-00014"},{"key":"e_1_2_13_29_1","unstructured":"S&G Biotech.S&G biotech nitinol stents[Internet]. Available from:https:\/\/www.sngbio.co.kr\/"},{"key":"e_1_2_13_30_1","unstructured":"Boston Medical Products.DUMONTMSilicone Airway Stents[Internet]. Available from:https:\/\/www.bosmed.com\/interventional\u2010pulmonology\/tracheobronxanetm\u2010dumontm\u2010tracheal\u2010and\u2010bronchial\u2010stents\/dumontm\u2010silicone\u2010airway\u2010stents\/"},{"key":"e_1_2_13_31_1","unstructured":"UptoDate.Reynders Noppen Tygon stent[Internet]. Available from:http:\/\/uptodate.dratef.net\/contents\/mobipreview.htm?10\/2\/10287"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-011-1762-0"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2020.0944"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1072"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.4997\/JRCPE.2020.409"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.18.2164"}],"container-title":["Clinical Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.13923","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/coa.13923","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.13923","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T03:23:26Z","timestamp":1692847406000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/coa.13923"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,5]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/coa.13923"],"URL":"https:\/\/doi.org\/10.1111\/coa.13923","archive":["Portico"],"relation":{},"ISSN":["1749-4478","1749-4486"],"issn-type":[{"value":"1749-4478","type":"print"},{"value":"1749-4486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,5]]},"assertion":[{"value":"2021-10-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}