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Rh\u2010bFGF nasal\u2010spray and drop application reduced general nasal VAS scores within 2\u2009weeks after endoscopic sinus surgery (ESS) compared to the control group. In contrast, only rh\u2010bFGF nasal\u2010drops reduced SNOT\u201022 scores at 2\u2009weeks and 1\u00a0year compared with the control group. A significant reduction in the endoscopic L\u2010K score was observed in the rh\u2010bFGF nasal\u2010spray and drop group compared with the control group. This is primarily because rh\u2010bFGF promotes cilia growth in the nasal mucosal epithelium after the operation, as illustrated by scanning electron microscopy and expression of CP110, Tap73 and Foxj1 mRNA. For eosinophilic CRSwNP, the general VAS score of rh\u2010bFGF nasal\u2010drops was more obviously reduced compared to the control group after ESS. A similar trend was observed for L\u2010K score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Rh\u2010bFGF nasal\u2010drops and sprays can quickly and effectively relieve postoperative symptoms and improve long\u2010term prognosis of patients with CRSwNP. Moreover, rh\u2010bFGF nasal\u2010drops is also an effective method for postoperative patients with eosinophilic CRSwNP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/coa.13955","type":"journal-article","created":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T05:49:30Z","timestamp":1657432170000},"page":"294-304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Therapeutic potential of recombinant human basic fibroblast growth factor on postoperative patients with chronic rhinosinusitis with nasal polyps"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3830-5689","authenticated-orcid":false,"given":"Jian","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Guangzhou Red Cross Hospital, Jinan University  Guangzhou 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