{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:41:27Z","timestamp":1772160087804,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100021528","name":"Royal Victorian Eye and Ear Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021528","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Transnasal esophagoscopy (TNE) in the awake patient and esophagogastroduodenoscopy (EGD) in sedation are both used in the assessment of laryngopharyngeal reflux (LPR). The objective of this study was to compare these two endoscopic methods in contributing to the diagnosis of LPR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study included 54 patients presenting with signs and symptoms suspicious for LPR, which were examined both by TNE and EGD. The contribution of each method to the diagnosis of LPR was evaluated separately and then compared with each other.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In detecting LPR, TNE showed a significant higher sensitivity (94% vs. 60%) and accuracy (93% vs. 59%) than EGD, but their specificity was equal (50% each). The most common pathologic findings in both methods were a hiatal hernia (70% vs. 48%) and gaping cardia (69% vs. 24%), followed by peptic esophagitis (41% vs. 24%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The value of EGD is limited in the workup of LPR, as sedation tends to mask the subtle findings in this kind of reflux disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/coa.14022","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:35:29Z","timestamp":1671496529000},"page":"213-219","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of transnasal esophagoscopy and sedated esophagogastroduodenoscopy in the assessment of laryngopharyngeal reflux"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0415-398X","authenticated-orcid":false,"given":"Lukas","family":"Horvath","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Kantonsspital Aarau  Aarau Switzerland"},{"name":"Department of Surgery, The University of Melbourne The Royal Victorian Eye and Ear Hospital  East Melbourne VIC Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karolos","family":"Fostiropoulos","sequence":"additional","affiliation":[{"name":"HNO\u2010Zentrum Nordwest  Muttenz Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuel","family":"Burri","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology University Medical Clinic, Kantonsspital Baselland  Liestal Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcel","family":"Kraft","sequence":"additional","affiliation":[{"name":"HNO\u2010Zentrum Nordwest  Muttenz Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0145561320971915"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599819827488"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.125760"},{"key":"e_1_2_11_5_1","first-page":"4363","article-title":"How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease\u2010related? World","volume":"18","author":"Bortoli N","year":"2012","journal-title":"J Gastroenterol"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2021.11.008"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10143188"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13721"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10112409"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2010.01092.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(94)70068-0"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(96)70092-5"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0016\u20105085(99)70280\u20105"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102007\u20101005504"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(99)70003-9"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/003655201317097245"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-921037"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-861476"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2015.56.6.1566"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2012.01.021"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0016-5107(03)00001-4"}],"container-title":["Clinical Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.14022","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/coa.14022","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.14022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T01:52:02Z","timestamp":1692323522000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/coa.14022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,27]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1111\/coa.14022"],"URL":"https:\/\/doi.org\/10.1111\/coa.14022","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/COA.14022\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14022\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14022\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14022\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14022\/v1\/decision1","asserted-by":"object"}]},"ISSN":["1749-4478","1749-4486"],"issn-type":[{"value":"1749-4478","type":"print"},{"value":"1749-4486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,27]]},"assertion":[{"value":"2022-07-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}