{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T03:54:36Z","timestamp":1783137276937,"version":"3.54.6"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T00:00:00Z","timestamp":1672617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the correlation between inflammatory markers (IM) and hearing loss (HL) in a large cohort of apparently healthy individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A cross sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tel\u2010Aviv Medical Center (a tertiary referral center) Inflammatory Survey Participants Individuals who attended the Tel\u2010Aviv Medical Center Inflammatory Survey (TAMCIS) for a routine annual health check.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Out of 2,500 individuals included in the final study cohort, 1,170 (47.3%) had some hearing impairment. Those with a hearing loss in 1 or both ears had significantly higher levels of neutrophils, lymphocytes, neutrophil\u2010to\u2010lymphocyte ratio, monocyte\u2010to\u2010lymphocyte ratio, and red blood cell counts. There was a difference between low\u2010 and high\u2010 frequencies losses associated with the inflammatory status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>IM levels were associated with the presence of a HL, supporting a link between inflammatory changes and hearing loss.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/coa.14026","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T09:16:45Z","timestamp":1671614205000},"page":"220-225","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Association of inflammatory markers with hearing loss in young adults"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1741-2074","authenticated-orcid":false,"given":"Udi","family":"Shapira","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel\u2010Aviv Sourasky Medical Center, Tel\u2010Aviv, Israel, affiliated with the Sackler Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadas","family":"Ben Assayag","sequence":"additional","affiliation":[{"name":"Departments \u2018C\u2019, \u2018D\u2019 and \u2018E\u2019 and Institute for Special Medical Examinations (MALRAM), Tel\u2010Aviv Sourasky Medical Center, Tel\u2010Aviv, Israel, affiliated with the Sackler Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5904-1291","authenticated-orcid":false,"given":"Omer J.","family":"Ungar","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel\u2010Aviv Sourasky Medical Center, Tel\u2010Aviv, Israel, affiliated with the Sackler Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ophir","family":"Handzel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel\u2010Aviv Sourasky Medical Center, Tel\u2010Aviv, Israel, affiliated with the Sackler Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rani","family":"Abu Eta","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel\u2010Aviv Sourasky Medical Center, Tel\u2010Aviv, Israel, affiliated with the Sackler Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ori","family":"Rogowski","sequence":"additional","affiliation":[{"name":"Departments \u2018C\u2019, \u2018D\u2019 and \u2018E\u2019 and Institute for Special Medical Examinations (MALRAM), Tel\u2010Aviv Sourasky Medical Center, Tel\u2010Aviv, Israel, affiliated with the Sackler Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Zeltser","sequence":"additional","affiliation":[{"name":"Departments \u2018C\u2019, \u2018D\u2019 and \u2018E\u2019 and Institute for Special Medical Examinations (MALRAM), Tel\u2010Aviv Sourasky Medical Center, Tel\u2010Aviv, Israel, affiliated with the Sackler Faculty of 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