{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T13:49:08Z","timestamp":1776952148879,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T00:00:00Z","timestamp":1697846400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the clinical features of sudden hearing loss (SHL) in patients with and without endolymphatic hydrops (EH), and to investigate the association between SHL with EH and M\u00e9ni\u00e8re's disease (MD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The clinical data of 63 SHL patients with first symptoms were evaluated retrospectively. Patients were separated into two groups based on the results of gadolinium\u2010enhanced magnetic resonance imaging: EH and non\u2010EH groups. Independent sample <jats:italic>t<\/jats:italic>\u2010test and <jats:italic>U<\/jats:italic>\u2010test were used to compare groups for continuous variables, and the chi\u2010squared test, corrected chi\u2010squared test and Bonferroni correction test were used to compare groups for binary and ordinal variables. The binary logistic regression model was utilised for univariate and multivariate analysis of follow\u2010up patient prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The EH and non\u2010EH groups contained 32 and 31 patients, respectively. The EH group had a higher prevalence of low\u2010tone descending hearing loss. Fifty\u2010one patients were followed for more than 2\u2009years. In the EH group, 11 and 15 patients were diagnosed with sudden sensorineural hearing loss (SSNHL) and MD, respectively, while in the non\u2010EH group, 24 patients were diagnosed with SSNHL and only one with MD. EH, low\u2010tone descending hearing loss and vertigo were risk factors for the diagnosis of MD in a subgroup univariate regression analysis of patients experiencing SHL. EH was found to be a risk factor for the progression of SHL into MD in a multifactor regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with SHL who have EH are more likely to present with low\u2010tone descending hearing loss. EH is a risk factor for the subsequent development of MD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/coa.14116","type":"journal-article","created":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T10:00:32Z","timestamp":1697882432000},"page":"117-123","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The value of gadolinium\u2010enhanced <scp>MRI<\/scp> in predicting the development of sudden hearing loss into M\u00e9ni\u00e8re's disease"],"prefix":"10.1111","volume":"49","author":[{"given":"Huimin","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, the First Affiliated Hospital Fujian Medical University  Fuzhou China"},{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital Fujian Medical University  Fuzhou China"},{"name":"Fujian Institute of 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