{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T16:26:39Z","timestamp":1781713599641,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,3,16]],"date-time":"2025-03-16T00:00:00Z","timestamp":1742083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005866","name":"Far Eastern Memorial Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005866","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to find biomarkers for assessing migrainous features, that is, migrainous headache, sensitivity to sound and light (phono\u2010 and photophobia) and visual aura in vestibular migraine (VM) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>University hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      A total of 400 definitive VM patients were classified into four groups based on the number of migrainous features. Group A (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200945) had one migrainous feature (migrainous headache). Group B (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200970) had migrainous headache along with phono\u2010 and photophobia, while Group C (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200955) had migrainous headache and visual aura. Those with all three migrainous features were categorised in Group D (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009230). Another 40 healthy subjects were also enrolled for comparison.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcomes Measure<\/jats:title>\n                    <jats:p>All subjects underwent an inner ear test battery comprising audiometry, cervical, ocular vestibular\u2010evoked myogenic potential (cVEMP, oVEMP) and caloric tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Significant difference in mean age was observed in Group A when compared to Groups B\u2013D, indicating that younger age might not be associated with the manifestation of all three migrainous features. No significant difference was observed among the four groups irrespective of gender and inner ear test battery. Via multivariate logistic regression, the oVEMP test (adjusted odds ratio, aOR\u2009=\u20092.60) was superior to the cVEMP test as a stronger indicator for the presence of phono\u2010 and photophobia. Conversely, the cVEMP test (aOR\u2009=\u20092.59) served as a stronger indicator for the presence of visual aura than the oVEMP test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The oVEMP test may act as a biomarker for phono\u2010 and photophobia, whereas the cVEMP test shows a strong capacity to predict visual aura.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/coa.14298","type":"journal-article","created":{"date-parts":[[2025,3,16]],"date-time":"2025-03-16T20:27:06Z","timestamp":1742156826000},"page":"712-718","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Correlating Migrainous Features With Vestibular\u2010Evoked Myogenic Potentials in Vestibular Migraine"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3851-2303","authenticated-orcid":false,"given":"Yun\u2010Chen","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Taipei Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation New Taipei, Taiwan &amp; School of Medicine Tzu Chi University  Hualien Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3194-5811","authenticated-orcid":false,"given":"Yi\u2010Ho","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Far Eastern Memorial Hospital  New Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1997.3710615.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000036903.22461.39"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23640"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811434073"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411434166"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/87.1.141"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2010.02.013"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200407000-00031"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2008.01283.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES-201644"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811425884"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-4137-8"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-0149-2"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.4.436"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70107-8"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES-2011-0428"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(97)00503-4"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0202-110"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002636"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200411000-00019"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181e8fb1a"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2009.03.003"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000665"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-09851-y"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.071582498"}],"container-title":["Clinical Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/coa.14298","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T06:11:55Z","timestamp":1748844715000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/coa.14298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,16]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/coa.14298"],"URL":"https:\/\/doi.org\/10.1111\/coa.14298","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/COA.14298\/v4\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14298\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14298\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14298\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14298\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14298\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14298\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/COA.14298\/v4\/response1","asserted-by":"object"}]},"ISSN":["1749-4478","1749-4486"],"issn-type":[{"value":"1749-4478","type":"print"},{"value":"1749-4486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,16]]},"assertion":[{"value":"2024-03-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}