{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T10:48:55Z","timestamp":1787482135792,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS\u20102025\u201000516950"],"award-info":[{"award-number":["RS\u20102025\u201000516950"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008005","name":"Yonsei University College of Medicine","doi-asserted-by":"publisher","award":["6\u20102024\u20100183"],"award-info":[{"award-number":["6\u20102024\u20100183"]}],"id":[{"id":"10.13039\/501100008005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to evaluate the olfactory and gustatory functions of patients with nasal septal deviation (NSD) and identify the factors associated with olfactory loss (OL) and gustatory loss (GL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and Setting<\/jats:title>\n                    <jats:p>Retrospective data analysis of cohort group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Two\u2010hundred fourteen adult patients with NSD at a tertiary hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Olfactory and gustatory functions were assessed using the psychophysical olfactory and gustatory function tests. The association of various demographic and clinical factors, including age, sex, NSD type, allergic sensitization status, presence of concha bullosa (CB), total serum immunoglobulin E (IgE) level, blood eosinophil count, and acoustic rhinometry parameters, with OL and GL was analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the patients, 20.6% (44\/214) and 16.4% (35\/213) had\n                      <jats:styled-content style=\"fixed-case\">OL<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">GL<\/jats:styled-content>\n                      , respectively. Patients with\n                      <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content>\n                      showed a significantly lower threshold, discrimination, and identification (\n                      <jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>\n                      ) score than those without\n                      <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content>\n                      (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012). Conversely, the\n                      <jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>\n                      score did not differ according to age group, sex,\n                      <jats:styled-content style=\"fixed-case\">NSD<\/jats:styled-content>\n                      type, or allergic sensitization status. Blood eosinophil count was inversely correlated with the\n                      <jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>\n                      score (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003), whereas nasal cavity volume, minimal cross\u2010sectional area, and serum\n                      <jats:styled-content style=\"fixed-case\">IgE<\/jats:styled-content>\n                      level were not correlated with the\n                      <jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>\n                      score. In the multivariable analysis, the presence of\n                      <jats:styled-content style=\"fixed-case\">CB<\/jats:styled-content>\n                      (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.029, odds ratio [\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      ]\u2009=\u20092.281) and a blood eosinophil count \u2265\u2009190 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.030,\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u2009=\u20092.155) were identified as significant factors associated with\n                      <jats:styled-content style=\"fixed-case\">OL<\/jats:styled-content>\n                      . No factors were significantly associated with\n                      <jats:styled-content style=\"fixed-case\">GL<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The presence of CB and a high blood eosinophil count are significant predictors of OL in patients with NSD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/coa.70042","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T04:26:20Z","timestamp":1759292780000},"page":"101-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence and Associated Factors of Olfactory and Gustatory Loss in Patients With Nasal Septal Deviation"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4848-5479","authenticated-orcid":false,"given":"Ja\u2010Yoon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2851-3225","authenticated-orcid":false,"given":"Hyung\u2010Ju","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Yonsei University College of Medicine  Seoul Republic of Korea"},{"name":"The Airway Mucus Institute, Yonsei University College of Medicine Severance Hospital  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1238-6396","authenticated-orcid":false,"given":"Chang\u2010Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Yonsei University College of Medicine  Seoul Republic of Korea"},{"name":"The Airway Mucus Institute, Yonsei University College of Medicine Severance Hospital  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1426-7534","authenticated-orcid":false,"given":"Min\u2010Seok","family":"Rha","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Yonsei University College of Medicine  Seoul Republic of Korea"},{"name":"The Airway Mucus Institute, Yonsei University College of Medicine Severance Hospital  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(86)80059-3"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/ccd.ccd_110_19"},{"issue":"1","key":"e_1_2_13_4_1","first-page":"21","article-title":"A Morphometric Consideration of Nasal Septal Deviations by People With Paranasal Complaints; 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