{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T04:39:09Z","timestamp":1775450349096,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T00:00:00Z","timestamp":1768694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T00:00:00Z","timestamp":1768694400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Frontal sinusitis is influenced by anatomical variations that impact sinus drainage pathways. Among these, frontal recess cells classified by the International Frontal Sinus Anatomy Classification (IFAC) and uncinate process variations play a key role. This study aimed to investigate the relationship between these anatomical structures and the development of frontal sinusitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study included 144 patients (70 with frontal sinusitis, 74 controls) who underwent paranasal sinus computed tomography (PNSCT). Frontal recess cells were evaluated according to the IFAC, and uncinate process variations were assessed using the Landsberg and Friedman classification. Frontal sinusitis severity was determined by the Lund\u2013Mackay scoring system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The prevalence of supra\u2010agger (SAC) and supra\u2010bullar cells (SBC) was significantly higher in the frontal sinusitis group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). A positive correlation was found between the presence of SAC, SBC and supra\u2010bullar frontal cells and frontal sinus Lund\u2013Mackay scores (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002, respectively). No significant association was observed between uncinate process variations and frontal sinusitis (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.167).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Frontal recess cells, particularly SAC and SBC, appear to increase susceptibility to frontal sinusitis, likely by impairing drainage. Recognition of these anatomical variations may improve surgical planning and management outcomes in patients with frontal sinusitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/coa.70086","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T05:48:48Z","timestamp":1768801728000},"page":"426-433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of Frontal Recess Anatomy and Uncinate Process Variations With Frontal Sinusitis: A\n                    <scp>CT<\/scp>\n                    \u2010Based Observational Study"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3681-5418","authenticated-orcid":false,"given":"Aykut","family":"Yankuncu","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Bingol State Hospital  Bingol Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1371-3644","authenticated-orcid":false,"given":"Ertu\u011frul Edebali","family":"Kurt","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Haydarpa\u015fa Numune Training and Research Hospital University of Health Sciences  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5703-6720","authenticated-orcid":false,"given":"Ay\u015fe \u00d6zlem","family":"Bal\u0131k","sequence":"additional","affiliation":[{"name":"Department of Radiology, Haydarpa\u015fa Numune Training and Research Hospital University of Health Sciences  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3125-732X","authenticated-orcid":false,"given":"Sema Zer","family":"Toros","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Haydarpa\u015fa Numune Training and Research Hospital University of Health Sciences  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5565-1711","authenticated-orcid":false,"given":"\u00c7i\u011fdem Tepe","family":"Karaca","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Haydarpa\u015fa Numune Training and Research Hospital University of Health Sciences  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22105"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-015-0932-6"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14010103"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.2500\/105065894781874278"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21738"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200112000-00008"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2018.04.010"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2012.26.3774"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1179550619884946"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otorri.2020.06.008"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989770005-6"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.04.012"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.131.3.230"},{"issue":"3","key":"e_1_2_12_15_1","first-page":"264","article-title":"Analysis of Frontal Cells According to International Frontal Sinus Anatomy Classification in Patients With Chronic Rhinosinusitis","volume":"18","author":"Uz U.","year":"2019","journal-title":"KBB\u2014Forum"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20977"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949510410s01"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-015-1459-y"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-4441-3"},{"issue":"3","key":"e_1_2_12_20_1","first-page":"145","article-title":"Concha Bullosa Types: Their Relationship With Sinusitis, Ostiomeatal and Frontal Recess Disease","volume":"11","author":"Hatipo\u011flu H. 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