{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:58:31Z","timestamp":1785776311824,"version":"3.56.0"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate functional oral intake and patient\u2010reported dysphagia, neck disability, and symptom\u2010specific health\u2010related quality of life (HRQOL) amongst patients who underwent pectoralis major myocutaneous flap (PMMF) versus microvascular free flap reconstruction after salvage laryngectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective analysis of prospectively collected data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Multidisciplinary head and neck cancer (HNC) Survivorship clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Patients with at least 6\u2009months of postoperative follow\u2010up from salvage total laryngectomy\/total laryngectomy with partial pharyngectomy and subsequent PMMF or free flap reconstruction were included. Patients who underwent total laryngo\u2010pharyngectomy, with recurrence, with metastatic disease, and\/or with missing data were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Functional Oral Intake Scale (FOIS) and validated patient\u2010reported outcome measures, including Eating Assessment Tool\u201010 (EAT\u201010), Neck Disability Index (NDI), and measures of pain\u2010, swallowing\u2010, and shoulder\u2010specific University of Washington Quality of Life (UW\u2010QOL) subscale scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010four patients underwent PMMF, and 30 patients underwent microvascular free flaps. Mean EAT\u201010, NDI, and pain\u2010, swallowing\u2010, and shoulder\u2010specific UW\u2010QOL subscale scores were not significantly different between these two groups. Mean FOIS was slightly higher in patients reconstructed with PMMF (5.67\u2009\u00b1\u20091.52 vs. 4.57\u2009\u00b1\u20092.12),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.047, but the clinical relevance of this finding is unclear.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patient\u2010reported outcomes pertaining to dysphagia, neck disability, and pain\u2010, swallowing\u2010 and shoulder\u2010specific HRQOL did not vary significantly between patients reconstructed with PMMF versus microvascular free flap. Future studies with larger cohorts are required to further establish differences in functional outcomes between reconstructive approaches following salvage laryngectomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/coa.70117","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:51:21Z","timestamp":1778820681000},"page":"687-693","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quality of Life Outcomes in Salvage Laryngectomy Reconstruction"],"prefix":"10.1111","volume":"51","author":[{"given":"Zainab","family":"Balogun","sequence":"first","affiliation":[{"name":"University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Mocharnuk","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fendi","family":"Obuekwe","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nia","family":"Buckner","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4721-4415","authenticated-orcid":false,"given":"Sophia","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010 Head and Neck Surgery University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5888-668X","authenticated-orcid":false,"given":"Marci L.","family":"Nilsen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010 Head and Neck Surgery University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010 Head and Neck Surgery University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaum","family":"Sridharan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010 Head and Neck Surgery University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4832-8422","authenticated-orcid":false,"given":"Mark","family":"Kubik","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010 Head and Neck Surgery University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2022.0016"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.112574"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0022215100132037"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199106133242402"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/88.13.890"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2017.10.009"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep46256"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1994.01880300047007"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002\u20109610(05)80096\u20100"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2013.08.018"},{"issue":"7","key":"e_1_2_13_12_1","first-page":"472","article-title":"Speech and Swallowing Function After Reconstruction With a Radial Forearm Free Flap or a Pectoralis Major Flap for Tongue Cancer","volume":"101","author":"Su W. 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