{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T03:03:55Z","timestamp":1789959835620,"version":"4.0.1"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:00:00Z","timestamp":1789862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:00:00Z","timestamp":1789862400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"abstract":"ABSTRACT<\/jats:title>\n \n Introduction<\/jats:title>\n Persistent postural\u2013perceptual dizziness (PPPD) is a chronic dizziness disorder in older adults, characterized by persistent non\u2010vertiginous dizziness and postural instability. This study aimed to investigate the associations of intrinsic capacity, sarcopenia and geriatric syndromes with PPPD in older adults.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This cross\u2010sectional study included 263 individuals aged over 65\u2009years (128 with PPPD and 135 without PPPD) attending geriatric and otorhinolaryngology outpatient clinics. PPPD was diagnosed according to B\u00e1r\u00e1ny Society criteria. Comprehensive geriatric assessment included intrinsic capacity domains, frailty (FRAIL scale), handgrip strength (HGS), sarcopenia parameters and history of falls. Multiple logistic regression models were constructed to evaluate independent associations while avoiding collinearity between overlapping variables. Separate models were used to assess physical performance, intrinsic capacity, sarcopenia and geriatric syndromes.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Participants with PPPD had significantly lower intrinsic capacity, slower gait speed, lower handgrip strength, higher depressive symptoms, higher frailty and more frequent falls (all\n p<\/jats:italic>\n \u2009\u2264\u20090.005). In locomotion\u2010based models, slower gait speed (OR\u2009=\u20090.121, 95% CI: 0.031\u20130.474;\n p<\/jats:italic>\n \u2009=\u20090.002), higher GDS\u201015 scores (OR\u2009=\u20091.131, 95% CI: 1.021\u20131.252;\n p<\/jats:italic>\n \u2009=\u20090.018) and fall history (OR\u2009=\u20092.660, 95% CI: 1.502\u20134.711;\n p<\/jats:italic>\n \u2009=\u20090.001) were independently associated with PPPD. In muscle strength models, lower handgrip strength was also associated with PPPD (OR\u2009=\u20090.927, 95% CI: 0.879\u20130.978;\n p<\/jats:italic>\n \u2009=\u20090.006). Domain\u2010based analysis showed that locomotor and psychological impairments were independently associated with PPPD. Lower intrinsic capacity was strongly associated with PPPD (OR\u2009=\u20090.497, 95% CI: 0.377\u20130.656;\n p<\/jats:italic>\n \u2009<\u20090.001). In clinically oriented models, probable sarcopenia (OR\u2009=\u20092.185, 95% CI: 1.188\u20134.018;\n p<\/jats:italic>\n \u2009=\u20090.012), frailty (OR\u2009=\u20092.381, 95% CI: 1.323\u20134.285;\n p<\/jats:italic>\n \u2009=\u20090.004) and depression (OR\u2009=\u20092.558, 95% CI: 1.387\u20134.717;\n p<\/jats:italic>\n \u2009=\u20090.003) were independently associated with PPPD, while malnutrition did not show a significant association.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n PPPD in older adults extends beyond a purely vestibular disorder, encompassing geriatric dimensions such as frailty, muscle weakness and depressive symptoms. An integrated otolaryngology\u2013geriatrics care model is warranted, and longitudinal studies evaluating the impact of geriatric interventions on PPPD's natural history are needed.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/coa.70170","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T02:48:55Z","timestamp":1789958935000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistent Postural\u2013Perceptual Dizziness in Older Adults: Associations With Intrinsic Capacity Decline, Probable Sarcopenia and Geriatric Syndromes"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6256-0351","authenticated-orcid":false,"given":"Nagihan S\u00f6zen","family":"Gencer","sequence":"first","affiliation":[{"name":"Division of Geriatrics, Department of Internal Medicine Bal\u0131kesir Atat\u00fcrk City Hospital Bal\u0131kesir Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4570-3071","authenticated-orcid":false,"given":"Sibel","family":"Cavdar","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Internal Medicine Izmir City Hospital \u0130zmir Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9828-4341","authenticated-orcid":false,"given":"Mehmet Fatih","family":"\u00d6zhan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Bal\u0131kesir Atat\u00fcrk City Hospital Bal\u0131kesir Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6822-2679","authenticated-orcid":false,"given":"Omer","family":"Hizli","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Faculty of Medicine Bal\u0131kesir University Bal\u0131kesir Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3233\/VES-170622","article-title":"Diagnostic Criteria for Persistent Postural\u2010Perceptual Dizziness (PPPD): Consensus Document of the Committee for the Classification of Vestibular Disorders of the B\u00e1r\u00e1ny Society","volume":"27","author":"Staab J. 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