{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T23:45:50Z","timestamp":1791762350048,"version":"4.3.4"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2504100"],"award-info":[{"award-number":["2022YFC2504100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271148"],"award-info":[{"award-number":["82271148"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82401331"],"award-info":[{"award-number":["82401331"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82401332"],"award-info":[{"award-number":["82401332"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Otolaryngology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Functional endoscopic sinus surgery (FESS) remains a primary treatment modality for chronic rhinosinusitis with nasal polyps (CRSwNP) refractory to medical management. This study aimed to evaluate the predictive value of routine preoperative examinations for early surgical outcomes following FESS in patients with CRSwNP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective cohort study evaluated whether routine preoperative assessments predict early outcomes after FESS in 181 patients with bilateral CRSwNP. Preoperative evaluations included Lund\u2013Mackay CT scores, Lund\u2013Kennedy endoscopy scores, symptom Visual Analogue Scale (VAS), SNOT\u201022 and peripheral blood eosinophil counts. Patients were followed postoperatively at 2\u2009weeks, 1, 3 and 6\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Preoperative VAS showed the strongest correlation with 2\u2010week symptom improvement (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.633), remaining an independent predictor in multivariate analysis (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.58). Preoperative SNOT\u201022 also independently predicted 2\u2010week outcomes (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.15). At 3\u2009months, blood eosinophil counts predicted endoscopic improvement (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.305), while preoperative Lund\u2013Kennedy scores strongly predicted 6\u2010month endoscopic outcomes (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.508).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Routine preoperative assessments provide valuable predictive information for early postoperative outcomes following FESS in CRSwNP. We expect these findings to support the integration of multimodal preoperative assessment to guide patient counselling and postoperative management expectations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/coa.70181","type":"journal-article","created":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T23:41:06Z","timestamp":1791762066000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive Value of Preoperative Examinations for Early Prognosis After Functional Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Nasal Polyps"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0362-5884","authenticated-orcid":false,"given":"Xinyi","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery The Third Affiliated Hospital of Sun Yat\u2010sen University  Guangzhou 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