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This systematic review evaluated cross\u2010sectional, short\u2010term (2\u201314 d), randomized and non\u2010randomized trials which reported on the effect of prescribed physical activity\/exercise on non\u2010exercise physical activity\/energy expenditure in healthy adults. <jats:styled-content style=\"fixed-case\">PubMed<\/jats:styled-content> and Embase were searched (from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 1990 to <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2013) for articles that presented data on the change in non\u2010exercise physical activity\/energy expenditure in response to prescribed physical activity\/exercise training. Thirty\u2010one articles were included in this review. One\u2010hundred per cent of cross\u2010sectional studies (<jats:italic>n<\/jats:italic>\u2009=\u20094), 90% of short\u2010term studies (<jats:italic>n<\/jats:italic>\u2009=\u200910), 50% of non\u2010randomized trials (<jats:italic>n<\/jats:italic>\u2009=\u200910) and 100% of randomized trials (<jats:italic>n<\/jats:italic>\u2009=\u20097) reported no reductions in non\u2010exercise physical activity\/energy expenditure in response to prescribed physical activity\/exercise training. We found minimal evidence to support the hypothesis that prescribed physical activity\/exercise training results in decreased non\u2010exercise physical activity\/energy expenditure in healthy adults. However, this literature is limited by the lack of adequately powered trials designed specifically to evaluate this hypothesis which have included assessments of both the energy expenditure of prescribed exercise and non\u2010exercise energy expenditure using state\u2010of\u2010the\u2010art techniques, i.e. indirect calorimetry and doubly labelled water, respectively.<\/jats:p>","DOI":"10.1111\/cob.12040","type":"journal-article","created":{"date-parts":[[2013,11,27]],"date-time":"2013-11-27T06:39:23Z","timestamp":1385534363000},"page":"1-20","source":"Crossref","is-referenced-by-count":64,"title":["Does increased prescribed exercise alter non\u2010exercise physical activity\/energy expenditure in healthy adults? A systematic review"],"prefix":"10.1111","volume":"4","author":[{"given":"R. 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