{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:40:47Z","timestamp":1790394047132,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,5,10]],"date-time":"2016-05-10T00:00:00Z","timestamp":1462838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Obesity"],"published-print":{"date-parts":[[2016,6]]},"abstract":"Summary<\/jats:title>Obesity and hypertension (HTN<\/jats:styled-content>) are major risk factors for cardiovascular disease. Association between obesity and HTN<\/jats:styled-content> has not been studied in a large populations following adjustment for comorbidities. The goal of this study was to evaluate any association between obesity and HTN<\/jats:styled-content> after adjusting for baseline characteristics. We used ICD<\/jats:styled-content>\u20109 codes for obesity and HTN<\/jats:styled-content> from the Nationwide Inpatient Sample (NIS<\/jats:styled-content>) databases. Two randomly selected years, 1992 and 2002, were chosen from the databases as two independent samples. We used uni\u2010 and multivariable analysis to study any correlation between obesity and HTN<\/jats:styled-content>. The 1992 database contained a total of 6,195,744 patients. HTN<\/jats:styled-content> was present in 37.2 % of patients with obesity versus 12% of the control group (OR<\/jats:styled-content>: 4.36, CI<\/jats:styled-content> 4.30\u20134.42, P<\/jats:italic>\u2009<\u20090.001). The 2002 database contained a total of 7,153,982 patients. HTN<\/jats:styled-content> was present in 50.7% of patients with obesity versus 25.6% of the control group (OR<\/jats:styled-content>: 2.98, CI<\/jats:styled-content> 2.96\u20133.00, P<\/jats:italic>\u2009<\u20090.001). Using multivariable analysis adjusting for gender, hyperlipidaemia, age, smoking, type 2 diabetes and chronic renal failure, obesity remained correlated with HTN<\/jats:styled-content> in both years (1992: OR<\/jats:styled-content> 2.69, CI<\/jats:styled-content> 2.67\u20132.72, P<\/jats:italic>\u2009<\u20090.001; 2002: OR<\/jats:styled-content> 2.98, CI<\/jats:styled-content> 2.96\u20133.00, P<\/jats:italic>\u2009<\u20090.001). The presence of obesity was found to be strongly and independently associated with HTN<\/jats:styled-content>. The cause of this correlation is not known warranting further investigation.<\/jats:p>","DOI":"10.1111\/cob.12139","type":"journal-article","created":{"date-parts":[[2016,5,11]],"date-time":"2016-05-11T02:39:20Z","timestamp":1462934360000},"page":"189-192","source":"Crossref","is-referenced-by-count":19,"title":["Strong independent association between obesity and essential hypertension"],"prefix":"10.1111","volume":"6","author":[{"given":"M. R.","family":"Movahed","sequence":"first","affiliation":[{"name":"CareMore HealthCare Tucson AZ USA"},{"name":"School of Medicine University of Arizona Tucson AZ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Z.","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Medicine University of Arizona Tucson AZ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Y.","family":"Lim","sequence":"additional","affiliation":[{"name":"Hurley Medical Center Flint MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hashemzadeh","sequence":"additional","affiliation":[{"name":"School of Medicine University of Arizona Tucson AZ USA"},{"name":"PIMA College Tucson AZ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hashemzadeh","sequence":"additional","affiliation":[{"name":"Long Beach VA Health Care System Long Beach CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,10]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"1","article-title":"Prevalence of obesity in the United States, 2009\u20132010","volume":"82","author":"Ogden CL","year":"2012","journal-title":"NCHS Data Brief"},{"key":"e_1_2_8_3_1","first-page":"1","article-title":"Changes in terminology for childhood overweight and obesity","volume":"25","author":"Ogden CL","year":"2010","journal-title":"Natl Health Stat Rep"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)61175-0"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.08.098"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2012.12.001"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu5041218"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.1.76"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2006.01262.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/1047-2797(90)90017-M"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2011.02.004"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-1-200101020-00007"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)06710-1"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.35.2.544"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2011.00914.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199715120-00074"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1994.267.2.E187"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2006.00569.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.650"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7176.2011.00578.x"}],"container-title":["Clinical Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcob.12139","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cob.12139","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T16:41:18Z","timestamp":1695746478000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cob.12139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,10]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["10.1111\/cob.12139"],"URL":"https:\/\/doi.org\/10.1111\/cob.12139","archive":["Portico"],"relation":{},"ISSN":["1758-8103","1758-8111"],"issn-type":[{"value":"1758-8103","type":"print"},{"value":"1758-8111","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,10]]}}}