{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:28:56Z","timestamp":1784687336923,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T00:00:00Z","timestamp":1551225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Obesity"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>The aim of this study was to evaluate the prevalence of hyperuricemia and acute gout after laparoscopic sleeve gastrectomy (LSG). Risk factors for developing gout were also examined. Eighty\u2010five patients underwent LSG were enrolled in this prospective study. Serum uric acid levels, gout attacks and total water levels % derived by bioimpedance were examined pre\u2010operatively and 1 month post\u2010operatively. Hyperuricemia was identified in 30.6% pre\u2010operatively and in 18.82% of patients post\u2010operatively. From the patients\u2019 group with pre\u2010operative hyperuricemia, 53.9% were normalized, 46.2% had increased uric acid post\u2010operatively while gout was observed in 11.5%. From the patients group without pre\u2010operative hyperuricemia, hyperuricemia and gout were observed in 6.8% and 5.1% post\u2010operatively, respectively. The relative risk for developing hyperuricemia was 6.2 (95% confidence interval [CI] 2.2\u201017.8) and for developing gout was 2.3 (95% CI 2.2\u201017.8). Statistical significant differences for gout among the groups with and without gout were indicated concerning pre\u2010operative use of medications (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), age (<jats:italic>P<\/jats:italic>\u2009=\u20090.025), post\u2010operative uric acid levels (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and post\u2010operative total water levels % (<jats:italic>P<\/jats:italic>\u2009=\u20090.048). The prevalence of hyperuricemia was 18.8% and gout attack of 7.1% 1 month after LSG. From the cohort of patients with pre\u2010operative hyperuricemia, a significant proportion normalized uric acid, while 11.5% developed gout. Patients without hyperuricemia pre\u2010operatively developed hyperuricemia and gout in 6.8% and 5.1% post\u2010operatively, respectively. The patients who had gout were younger and had 37% water levels post\u2010operatively.<\/jats:p>","DOI":"10.1111\/cob.12296","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T07:46:06Z","timestamp":1551339966000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Hyperuricemia and acute gout after laparoscopic sleeve gastrectomy"],"prefix":"10.1111","volume":"9","author":[{"given":"Georgia","family":"Katsogridaki","sequence":"first","affiliation":[{"name":"Department of Surgery University Hospital of Larissa, University of Thessaly  Larissa Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Tzovaras","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Larissa, University of Thessaly  Larissa Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Sioka","sequence":"additional","affiliation":[{"name":"Department of Surgery Iaso Thessalias  Larissa Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Perivoliotis","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Larissa, University of Thessaly  Larissa Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Zachari","sequence":"additional","affiliation":[{"name":"Department of Surgery Iaso Thessalias  Larissa Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5417-6392","authenticated-orcid":false,"given":"Dimitrios","family":"Magouliotis","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Larissa, University of Thessaly  Larissa Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassiliki","family":"Tasiopoulou","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Larissa, University of Thessaly  Larissa Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0107-3976","authenticated-orcid":false,"given":"Dimitrios","family":"Zacharoulis","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Larissa, University of Thessaly  Larissa Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,27]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"98","article-title":"Hyperuricemia as a potential determinant of metabolic syndrome","volume":"3","author":"Yadav D","year":"2013","journal-title":"J Lifestyle 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