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The main way of mitigating these risks in obesity is with weight loss, which has been shown to positively affect the cardiorespiratory fitness (CRF) and body composition of adults. However, it is unclear whether the response of these outcomes to weight loss may be influenced by age of obesity onset. The objective of our study was to investigate how age of obesity onset mitigates the responsiveness of CRF, muscle strength and body composition to modest weight loss. Measurements were conducted at baseline and 12\u2009weeks. In total, 37 participants (childhood\u2010onset\u2009=\u200919, adult\u2010onset\u2009=\u200918) lost 3.7%\u2009\u00b1\u20090.4% through aerobic exercise and diet. The YMCA cycle ergometer test (YMCA) and the 20\u2010m shuttle run test (20MSR) were used to estimate CRF (mL\u2009kg<jats:sup>\u22121<\/jats:sup>\u2009min<jats:sup>\u22121<\/jats:sup>) and a handgrip dynamometer was used to estimate muscle strength. Total body composition was assessed by dual\u2010energy x\u2010ray absorptiometry (DEXA). Overall, CRF and body composition improved (time effect: <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) after 12\u2009weeks. There was no group\u2010by\u2010time interaction for YMCA, 20MSR, muscle strength and body composition variables. Therefore, the present study suggests that individuals with childhood\u2010onset obesity and adult\u2010onset obesity can improve their CRF and body composition similarly after mild weight loss.<\/jats:p>","DOI":"10.1111\/cob.12623","type":"journal-article","created":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T19:27:14Z","timestamp":1696534034000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Improvements in cardiorespiratory fitness, muscle strength and body composition to modest weight loss are similar in those with adult\u2010 versus childhood\u2010onset obesity"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9619-699X","authenticated-orcid":false,"given":"Lucas Guimar\u00e3es","family":"Almeida","sequence":"first","affiliation":[{"name":"Department of Health, Kinesiology, and Applied Physiology Concordia University  Montreal Quebec Canada"},{"name":"Metabolism, Obesity, and Nutrition Lab, School of Health Concordia University  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6378-6977","authenticated-orcid":false,"given":"Abdulrahman","family":"Dera","sequence":"additional","affiliation":[{"name":"Department of Health, Kinesiology, and Applied Physiology Concordia University  Montreal Quebec Canada"},{"name":"Metabolism, Obesity, and Nutrition Lab, School of Health Concordia University  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8071-4457","authenticated-orcid":false,"given":"Jessica","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Health, Kinesiology, and Applied Physiology Concordia University  Montreal Quebec Canada"},{"name":"Metabolism, Obesity, and Nutrition Lab, School of Health Concordia University  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5814-6086","authenticated-orcid":false,"given":"Sylvia","family":"Santosa","sequence":"additional","affiliation":[{"name":"Department of Health, Kinesiology, and Applied Physiology Concordia University  Montreal Quebec Canada"},{"name":"Metabolism, Obesity, and Nutrition Lab, School of Health Concordia University  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,4]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Obesity and overweight fact sheet #311: World Health Organization Media Centre; 2011. 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