{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:25:38Z","timestamp":1753878338750,"version":"3.41.2"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T00:00:00Z","timestamp":1723161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Obesity"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In the backdrop of the global obesity pandemic, recognized as a notable risk factor for coronavirus disease 2019 (COVID\u201019) complications, the study aims to explore clinical and epidemiological attributes of hospitalized COVID\u201019 patients throughout 2021 in Brazil. Focused on four distinct age cohorts, the investigation scrutinizes parameters such as intensive care unit (ICU) admission frequency, invasive mechanical ventilation (IMV) usage, and in\u2010hospital mortality among individuals with and without obesity. Using a comprehensive cross\u2010sectional study methodology, encompassing adult COVID\u201019 cases, data sourced from the Influenza Epidemiological Surveillance Information System comprises 329\u2009206 hospitalized patients. Of these individuals, 26.3% were affected by obesity. Analysis reveals elevated rates of ICU admissions, increased dependence on IMV, and heightened in\u2010hospital mortality among the individuals with obesity across all age groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Logistic regression, adjusting for confounding variables, underscores a progressively rising odds ratio for mortality in younger age brackets: 1.2 (95%CI 1.1\u20131.3) for those under 50\u2009years, 1.1 (95%CI 1.0\u20131.2) for the 50\u201359 age group, and 1.1 (95%CI 1.0\u20131.2) for the 60\u201369 age group. Conversely, no significant mortality difference is observed for patients over 70\u2009years (OR: 0.972, 95%CI 0.9\u20131.1). In summary, hospitalized COVID\u201019 patients with obesity, particularly in younger age groups, exhibit elevated rates of ICU admission, IMV requirement, and in\u2010hospital mortality compared with the control group. Notably, the \u2018obesity paradox\u2019 is not evident among hospitalized COVID\u201019 patients in 2021.<\/jats:p>","DOI":"10.1111\/cob.12698","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T20:27:15Z","timestamp":1723235235000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Associations between obesity and severity of coronavirus disease 2019 in Brazilian inpatients: A 2021 secondary data analysis"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8430-3599","authenticated-orcid":false,"given":"Gabrielle Ribeiro","family":"Sena","sequence":"first","affiliation":[{"name":"Department of Education and Research Instituto de Medicina Integral Professor Fernando Figueira \u2013 IMIP  Recife Brazil"},{"name":"Department of Education and Research Universidade de Pernambuco \u2013 UPE  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1148-4288","authenticated-orcid":false,"given":"Tiago Pessoa Ferreira","family":"de Lima","sequence":"additional","affiliation":[{"name":"Department of Education and Research Instituto Federal de Pernambuco\u2010 IFPE  Palmares Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2573-9958","authenticated-orcid":false,"given":"Michelle Lima","family":"de Carvalho Silva","sequence":"additional","affiliation":[{"name":"Department of Education and Research Faculdade Pernambucana de Sa\u00fade \u2013 FPS  Recife Brazil"},{"name":"Scientific Initiation Program Instituto de Medicina Integral Professor Fernando Figueira \u2013 IMIP  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paloma Gomes Tavares","family":"Sette","sequence":"additional","affiliation":[{"name":"Department of Education and Research Faculdade Pernambucana de Sa\u00fade \u2013 FPS  Recife Brazil"},{"name":"Scientific Initiation Program Instituto de Medicina Integral Professor Fernando Figueira \u2013 IMIP  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2398-5753","authenticated-orcid":false,"given":"Gabriela Carla","family":"dos Santos Costa","sequence":"additional","affiliation":[{"name":"Department of Education and Research Hospital Alfa  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Mendes","family":"da Fonseca Benvindo","sequence":"additional","affiliation":[{"name":"Department of Education and Research Hospital Alfa  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4645-8343","authenticated-orcid":false,"given":"Maria J\u00falia Gon\u00e7alves","family":"de Mello","sequence":"additional","affiliation":[{"name":"Department of Education and Research Instituto de Medicina Integral Professor Fernando Figueira \u2013 IMIP  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3699-0590","authenticated-orcid":false,"given":"Guilherme Jorge","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Education and Research Instituto de Medicina Integral Professor Fernando Figueira \u2013 IMIP  Recife Brazil"},{"name":"Department of Education and Research Hospital Alfa  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13128"},{"key":"e_1_2_8_3_1","unstructured":"World Health Organization. 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