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Since 2015, studies using continuous glucose monitoring (CGM) have revealed a more complex glycemic profile following metabolic bariatric surgery (MBS) characterised by CGM\u2010detected asymptomatic and nocturnal low interstitial glucose values, frequently occurring during prolonged intermeal periods, along with increased 24\u2010h glycemic variability. Provocative tests are limited by non\u2010physiological stimuli or poor standardisation. Meanwhile, although diagnostic workups for alternative etiologies not related to diabetes are recommended, these conditions are exceedingly rare compared with real\u2010world CGM\u2010detected events. Evidence from cohorts of individuals with diabetes links CGM metrics, such as nocturnal and prolonged intermeal low glucose exposure and glycemic variability, to adverse outcomes, including cardiovascular mortality, stroke, arrhythmias, next\u2010day cognitive slowing, retinopathy, microalbuminuria, and arterial stiffness. These findings may support the potential prognostic relevance of similar phenotypes following MBS. We argue for: (1) a critical revision of diagnostic criteria, including standardised interstitial thresholds, event definitions, and the role of symptoms; and (2) prospective CGM cohorts of post\u2010MBS patients without diabetes adequately sized to assess clinically meaningful endpoints, such as cardiovascular, microvascular, and cognitive outcomes. CGM has uncovered a likely blind spot in PBH, particularly asymptomatic and nocturnal hypoglycemia. Recognising this spectrum and aligning definitions, diagnostics, and care may improve outcomes.<\/jats:p>","DOI":"10.1111\/cob.70090","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:04:18Z","timestamp":1781741058000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypoglycemia in the Context of Post\u2010Bariatric Clinical Follow\u2010Up: Is There a Blind Spot in Research and Care?"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9216-7200","authenticated-orcid":false,"given":"Daniel","family":"Sant\u2019Anna da Silva","sequence":"first","affiliation":[{"name":"Postgraduate Program in Clinical and Experimental Physiopathology, Faculty of Medical Sciences State University of Rio de Janeiro  Rio de Janeiro Brazil"},{"name":"Obesity Unit, Multiuser Clinical Research Center, Pedro Ernesto University Hospital State University of Rio de 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