{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:14:46Z","timestamp":1772223286706,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T00:00:00Z","timestamp":1381536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Adverse drug reactions pose an increasing diagnostic challenge in hospitals and in outpatient clinics. When consecutive or repeated allergic drug eruptions are suspected, patch testing is a useful diagnostic tool for determining the causative drugs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of the study was to identify patient cases with multiple delayed\u2010type drug sensitizations by using patch testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eight hundred and eleven patients with suspected drug allergy were patch tested during a 9\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Multiple delayed drug sensitizations were found in 12% of those patients with positive results in drug patch testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Drug patch testing is useful in cutaneous adverse drug reactions where multiple drugs are suspected. Multiple drug sensitizations can be found in a proportion of patients who have delayed drug allergies. In addition to drug reactions with eosinophilia and systemic symptoms, these patients may have repeated exanthemas or contact dermatitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12076","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T09:32:20Z","timestamp":1444728740000},"page":"296-302","source":"Crossref","is-referenced-by-count":10,"title":["Patch testing and sensitization to multiple drugs"],"prefix":"10.1111","volume":"69","author":[{"given":"Jussi","family":"Liippo","sequence":"first","affiliation":[{"name":"Department of Dermatology Turku University Hospital  20521 Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kati","family":"Pummi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Turku University Hospital  20521 Turku Finland"},{"name":"Department of Pathology Turku University Hospital  20521 Turku 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