{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T05:33:05Z","timestamp":1791955985351,"version":"4.3.4"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T00:00:00Z","timestamp":1379548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2013,12]]},"abstract":"Summary<\/jats:title>Background<\/jats:title>Oak moss absolute (Evernia prunastri<\/jats:italic> extract) contains a large number of substances, among them the potent allergens atranol and chloroatranol. Since 2008, their content in oak moss absolute has been restricted by the I<\/jats:styled-content>nternational F<\/jats:styled-content>ragrance A<\/jats:styled-content>ssociation to a maximum level of 100\u2009ppm each.<\/jats:p><\/jats:sec>Objectives<\/jats:title>To compare the elicitation capacities of a traditional (sample A<\/jats:styled-content>) and a treated (sample B<\/jats:styled-content>) oak moss absolute containing, in total, 27\u2009000 and 66\u2009ppm of atranol and chloroatranol, respectively, and to investigate reactions to components of oak moss absolute separated by thin\u2010layer chromatography (TLC<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>Fifteen oak moss\u2010allergic subjects were patch tested with serial dilutions and TLC<\/jats:styled-content> strips of samples A<\/jats:styled-content> and B<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>Fifteen subjects reacted to sample A<\/jats:styled-content> at concentrations \u2264\u20092.0%, and 2 subjects reacted to sample B<\/jats:styled-content> at 2.0% but not to lower concentrations. Among 13 subjects reacting to the TLC<\/jats:styled-content> strip of sample A<\/jats:styled-content>, 11 reacted to spots with retardation factor values corresponding to those of atranol and\/or chloroatranol, and 11 reacted to other areas on the TLC<\/jats:styled-content> strip. Only one subject reacted to the TLC<\/jats:styled-content> strip of sample B<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The patch test reactivity of sample B<\/jats:styled-content> was significantly lower than that of sample A<\/jats:styled-content>. The TLC<\/jats:styled-content> patch tests indicate the presence of sensitizers other than atranol and chloroatranol in oak moss absolute.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12126","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T15:23:54Z","timestamp":1381245834000},"page":"342-349","source":"Crossref","is-referenced-by-count":20,"title":["Patch testing with serial dilutions and thin\u2010layer chromatograms of oak moss absolutes containing high and low levels of atranol and chloroatranol"],"prefix":"10.1111","volume":"69","author":[{"given":"Martin","family":"Mowitz","sequence":"first","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University SE\u201020502 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Zimerson","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University SE\u201020502 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Svedman","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University SE\u201020502 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Bruze","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University SE\u201020502 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,9,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640050083012"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2010.01759.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-003-0426-3"},{"key":"e_1_2_7_5_1","first-page":"27","article-title":"Formation of volatile compounds from Oakmoss","volume":"18","author":"Boelens M H","year":"1993","journal-title":"Perf Flav"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ffj.1916"},{"key":"e_1_2_7_7_1","first-page":"59","article-title":"Regulation (EC) No. 1223\/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products","volume":"342","year":"2009","journal-title":"Off J Eur Union"},{"key":"e_1_2_7_8_1","unstructured":"International Fragrance Association.Code of practice 43rd Amendment. 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