{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:21:48Z","timestamp":1791073308413,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,21]],"date-time":"2014-02-21T00:00:00Z","timestamp":1392940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Coconut fatty acids diethanolamide [cocamide diethanolamine (cocamide <jats:styled-content style=\"fixed-case\">DEA<\/jats:styled-content>)] is a surface\u2010active derivative of coconut oil that is used in industrial, household and cosmetic products. Cocamide <jats:styled-content style=\"fixed-case\">DEA<\/jats:styled-content> contact allergy has been reported relatively seldom.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe cocamide <jats:styled-content style=\"fixed-case\">DEA<\/jats:styled-content>\u2010positive patients in an occupational dermatology clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrieved allergic reactions to cocamide <jats:styled-content style=\"fixed-case\">DEA<\/jats:styled-content> from test files, and studied the occupation, exposure, concomitant allergic reactions and diagnoses of the positive patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 2572 patients tested, 25 (1%) had an allergic reaction to cocamide <jats:styled-content style=\"fixed-case\">DEA<\/jats:styled-content>. Nineteen patients were occupational cases, and 11 worked in the metal industry. Hand cleansers constituted the main source of sensitization (n\u2009=\u200917). Other sources included two dishwashing liquids, one barrier cream, and one metalworking fluid. Three patients reacted to monoethanolamine and 2 to diethanolamine. Diethanolamine is an impurity of cocamide <jats:styled-content style=\"fixed-case\">DEA<\/jats:styled-content>, and can be found in cocamide <jats:styled-content style=\"fixed-case\">DEA<\/jats:styled-content>\u2010containing products and in commercial patch test substances, which may explain some concomitant reactions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cocamide <jats:styled-content style=\"fixed-case\">DEA<\/jats:styled-content> allergy is relatively common in patients with occupational hand dermatitis, and mainly derives from hand cleansers. However, exposure to detergents, metalworking fluids and barrier creams must also be taken into account. Concomitant reactions to ethanolamines are possible.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12151","type":"journal-article","created":{"date-parts":[[2014,2,22]],"date-time":"2014-02-22T08:52:19Z","timestamp":1393059139000},"page":"169-174","source":"Crossref","is-referenced-by-count":34,"title":["Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide"],"prefix":"10.1111","volume":"70","author":[{"given":"Kristiina","family":"Aalto\u2010Korte","sequence":"first","affiliation":[{"name":"Control of Hypersensitivity Diseases Finnish Institute of Occupational Health (FIOH) Helsinki FI\u201000250 Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Pesonen","sequence":"additional","affiliation":[{"name":"Control of Hypersensitivity Diseases Finnish Institute of Occupational Health (FIOH) Helsinki FI\u201000250 Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Outi","family":"Kuuliala","sequence":"additional","affiliation":[{"name":"Control of Hypersensitivity Diseases Finnish Institute of Occupational Health (FIOH) Helsinki FI\u201000250 Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katri","family":"Suuronen","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine Finnish Institute of Occupational Health (FIOH) Helsinki FI\u201000250 Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,21]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"International Cosmetic Ingredient Dictionary and Handbook","author":"Wenninger J A","year":"2000"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1046-199X(98)90144-0"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1983.tb04347.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.2340\/0001555573126129","article-title":"Dentist's occupational allergic contact dermatitis caused by coconut diethanolamide, N\u2010ethyl\u20104\u2010toluene sulfonamide and 4\u2010tolyldiethanolamine","volume":"73","author":"Kanerva L","year":"1993","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1980.tb05583.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1993.tb03562.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1987.tb01401.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.0548n.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1991.tb01660.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1992.tb05256.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","DOI":"10.1111\/cod.12107","article-title":"Contact allergy from metal\u2010working fluid traced to tall oil fatty acids monoethanolamide","author":"Aalto\u2010Korte K","year":"2013","journal-title":"Contact Dermatitis"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.02036.x"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12151","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.12151","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T00:16:59Z","timestamp":1696637819000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.12151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,21]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/cod.12151"],"URL":"https:\/\/doi.org\/10.1111\/cod.12151","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,21]]}}}