{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T19:36:22Z","timestamp":1783020982204,"version":"3.54.6"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,12,11]],"date-time":"2013-12-11T00:00:00Z","timestamp":1386720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The thinness of the periorbital skin may facilitate allergen penetration, making this area particularly susceptible to sensitization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>For the cross\u2010sectional study, data were collected by the 57 participating centres of the <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nformation <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>etwork of <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epartments of <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ermatology. A total of 101\u2009403 patients patch tested between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2001 and <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2010 were included. Of these, 4779 patients suffered from periorbital dermatitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two major subgroups with different general epidemiological data and sensitization to specific allergens have to be considered: (i) young females with increased rates of skin atopy and allergies, particularly from cosmetic and skin care products; and (ii) older subjects with allergy to topical medications. The prevalence of sensitization to ophthalmic allergens is generally less than that to environmental allergens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Allergic contact dermatitis is a leading cause of periorbital dermatitis. Patch testing should be considered in all patients with periorbital dermatitis when contact allergy is suspected, in order to identify and avoid offending allergens.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12157","type":"journal-article","created":{"date-parts":[[2013,12,11]],"date-time":"2013-12-11T06:08:43Z","timestamp":1386742123000},"page":"205-212","source":"Crossref","is-referenced-by-count":39,"title":["Periorbital dermatitis in 4779 patients\u2009\u2013\u2009patch test results during a\u00a010\u2010year period"],"prefix":"10.1111","volume":"70","author":[{"given":"Lilla","family":"Landeck","sequence":"first","affiliation":[{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck 49090 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swen M.","family":"John","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck 49090 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Geier","sequence":"additional","affiliation":[{"name":"The Information Network of Departments of Dermatology (IVDK) University of G\u00f6ttingen G\u00f6ttingen 37075 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,11]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"11","article-title":"Contact allergic reactions on the eyes and eyelids","volume":"292","author":"Goossens A","year":"2004","journal-title":"Bull Soc Belge Ophtalmol"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.00334.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.122736"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(89)70165-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1992.tb05242.x"},{"key":"e_1_2_7_7_1","first-page":"36","article-title":"Epidemiology of contact dermatitis. 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