{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:21:07Z","timestamp":1791073267413,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T00:00:00Z","timestamp":1394755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hair dye products constitute an important source of allergen exposure, and contribute importantly to allergic contact dermatitis in consumers and hairdressers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the presence of potent contact sensitizers in oxidative hair dye products intended for home use on the<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>market.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ingredient labels of 107 hair dyes from 10 major brands were examined and used to assess the prevalence of hair dye substances known to be potent contact sensitizers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and six of 107 (99%) products contained at least one potent sensitizer, and the average product contained six (range 0\u201311).<jats:italic>p<\/jats:italic>\u2010Phenylenediamine (<jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content>) was found in 83 products (78%), but resorcinol (89%),<jats:italic>m<\/jats:italic>\u2010aminophenol (75%),<jats:italic>p<\/jats:italic>\u2010aminophenol (60%) and toluene\u20102,5\u2010diamine (21%) were also frequently identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Potent contact sensitizers were almost universally included in the hair dyes investigated in the<jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>nited<jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tates. Although<jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content>is a common allergen, resorcinol and<jats:italic>m<\/jats:italic>\u2010aminophenol were found more frequently. In total, 30 potent sensitizers were found. Clinicians should consider other allergens in addition to<jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content>when evaluating patients with suspected hair dye allergy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12164","type":"journal-article","created":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T08:27:42Z","timestamp":1394785662000},"page":"213-218","source":"Crossref","is-referenced-by-count":71,"title":["<i>p<\/i>\u2010<scp>P<\/scp>henylenediamine and other allergens in hair dye products in the<scp>U<\/scp>nited<scp>S<\/scp>tates: a consumer exposure study"],"prefix":"10.1111","volume":"70","author":[{"given":"Dathan","family":"Hamann","sequence":"first","affiliation":[{"name":"University of Arizona College of Medicine\u2009\u2013\u2009Phoenix Phoenix AZ 85004 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerem","family":"Yazar","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine, Karolinska Institutet SE\u2010171 77 Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten R.","family":"Hamann","sequence":"additional","affiliation":[{"name":"Loma Linda University School of Medicine Loma Linda CA 92350 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob P.","family":"Thyssen","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Allergology Copenhagen University Hospital Gentofte, Niels Andersens Vej 65 DK\u20102900 Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carola","family":"Lid\u00e9n","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine, Karolinska Institutet SE\u2010171 77 Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,14]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2310\/6620.2009.08089","article-title":"Consumer allergy to oxidative hair coloring products: epidemiologic data in the literature","volume":"20","author":"Krasteva M","year":"2009","journal-title":"Dermatitis"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2009.01612.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01979.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01427.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/15569527.2011.641195"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408440701385671"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1179\/027249309X12467994693815"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2002.470508.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.5402\/2011\/947284"},{"key":"e_1_2_5_11_1","unstructured":"European Commission Scientific Committee on Consumer Products.Memorandum on hair dye substances and their skin sensitizing properties 2007. 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