{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:21:48Z","timestamp":1791073308972,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T00:00:00Z","timestamp":1412899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Danish Working Environment Research Fund","award":["21-2009-09"],"award-info":[{"award-number":["21-2009-09"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Irritant contact dermatitis (<jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>) is a common diagnosis in patients with occupational contact dermatitis (<jats:styled-content style=\"fixed-case\">OCD<\/jats:styled-content>). Studies are lacking on the usefulness of material safety data sheets (<jats:styled-content style=\"fixed-case\">MSDS<\/jats:styled-content>s) in making the diagnosis of <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To characterize irritant exposures leading to the diagnosis of occupational <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OICD<\/jats:styled-content>), and to evaluate the occurrence of concomitant exposures to contact allergens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 316 patients with suspected occupational hand dermatitis, referred to the <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epartment of <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ermato\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>llergology, <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>openhagen <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>entofte, <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>enmark during <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2010\u2013<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ugust 2011, in a programme consisting of a clinical examination, exposure assessment, and extensive patch\/prick testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">OCD<\/jats:styled-content> was diagnosed in 228 patients. Of these patients, 118 were diagnosed with <jats:styled-content style=\"fixed-case\">OICD<\/jats:styled-content>. The main irritant exposures identified were wet work (n = 64), gloves (n = 45), mechanical traumas (n = 19), and oils (n = 15). Exposure to specific irritant chemicals was found in 9 patients, and was identified from <jats:styled-content style=\"fixed-case\">MSDS<\/jats:styled-content>s\/ingredients labelling in 8 of these patients. Review of <jats:styled-content style=\"fixed-case\">MSDS<\/jats:styled-content>s and ingredients labelling showed that 41 patients were exposed to 41 moderate to potent contact allergens, and 18 patients were exposed to 25 weak workplace contact allergens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the present study, the systematic exposure assessment did not reveal any new irritants. <jats:styled-content style=\"fixed-case\">MSDS<\/jats:styled-content>s have a limited role in the investigation of <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12290","type":"journal-article","created":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T04:51:30Z","timestamp":1412916690000},"page":"364-370","source":"Crossref","is-referenced-by-count":40,"title":["Occupational irritant contact dermatitis diagnosed by analysis of contact irritants and allergens in the work environment"],"prefix":"10.1111","volume":"71","author":[{"given":"Ulrik F.","family":"Friis","sequence":"first","affiliation":[{"name":"Department of Dermato\u2010Allergology National Allergy Research Centre, Copenhagen University Hospital Gentofte  2900 Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torkil","family":"Menn\u00e9","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Allergology National Allergy Research Centre, Copenhagen University Hospital Gentofte  2900 Hellerup Denmark"},{"name":"Department of Dermato\u2010Allergology Copenhagen University Hospital Gentofte  2900 Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob F.","family":"Schwensen","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Allergology National Allergy Research Centre, Copenhagen University Hospital Gentofte  2900 Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari\u2010Ann","family":"Flyvholm","sequence":"additional","affiliation":[{"name":"The National Research Centre for the Working Environment  2100 Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens P. E.","family":"Bonde","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Copenhagen University Hospital Bispebjerg  2400 Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne D.","family":"Johansen","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Allergology National Allergy Research Centre, Copenhagen University Hospital Gentofte  2900 Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01915.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12102"},{"key":"e_1_2_6_4_1","unstructured":"Bundesanstalt f\u00fcr Arbeitsschutz und Arbeitsmedizin (BAuA).Risks resulting from skin contact \u2013 identification assessment measures \u2013 TRGS 401 2008. Available at:http:\/\/www.baua.de\/en\/Topics\u2010from\u2010A\u2010to\u2010Z\/Hazardous\u2010Substances\/TRGS\/pdf\/TRGS\u2010401.pdf?__blob=publicationFile&v=6(last accessed 05 April 2014)."},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-02035-3_74"},{"key":"e_1_2_6_6_1","first-page":"287","article-title":"Terminology of contact dermatitis","volume":"50","author":"Wilkinson D S","year":"1970","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.02048.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.02004_3.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.02004_4.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2009.01607.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-31301-X_13"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01231.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-03827-3_16"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1999.tb06162.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1996.tb02196.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-009-0980-4"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12097"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12288"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09245.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0048678"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09822.x"},{"key":"e_1_2_6_22_1","article-title":"Challenges in using MSDS for analysis of occupational exposures to contact allergens","author":"Friis U F","year":"2014","journal-title":"Contact Dermatitis"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01882.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.00423.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06415.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12134"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12290","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.12290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T16:46:53Z","timestamp":1696351613000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.12290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,10]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/cod.12290"],"URL":"https:\/\/doi.org\/10.1111\/cod.12290","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,10]]}}}