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Prick tests were performed with chemical solutions and human serum albumin (<jats:styled-content style=\"fixed-case\">HSA<\/jats:styled-content>)\u2013chemical conjugates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Positive prick test reactions to isocyanate\u2013<jats:styled-content style=\"fixed-case\">HSA<\/jats:styled-content>conjugates were associated with isocyanate\u2010specific<jats:styled-content style=\"fixed-case\">IgE<\/jats:styled-content>in all 20 patients, and 17 patients had a relevant occupational disease. Positive reactions to chloramine\u2010<jats:styled-content style=\"fixed-case\">T\u2013HSA<\/jats:styled-content>conjugates in 10 patients also indicated the presence of specific<jats:styled-content style=\"fixed-case\">IgE<\/jats:styled-content>, although occupational diseases were not always diagnosed. Eleven of 17 patients with positive reactions to persulfate solutions were diagnosed with an occupational disease. Methacrylates, colophonium\u2010related substances, amine hardeners, ethanolamines, glutaraldehyde, glyoxal, pyrocatechol and ammonium thioglycolate did not elicit any relevant prick test reactions. No generalized reactions were detected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Prick tests can be safely used for diagnosing contact urticaria, asthma and rhinitis caused by isocyanates, chloramine\u2010<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>, persulfates, and chlorhexidine, but the results should be carefully interpreted and related to clinical symptoms and other diagnostic tests.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12308","type":"journal-article","created":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T12:53:57Z","timestamp":1412686437000},"page":"20-32","source":"Crossref","is-referenced-by-count":51,"title":["Prick testing with chemicals in the diagnosis of occupational contact urticaria and respiratory diseases"],"prefix":"10.1111","volume":"72","author":[{"given":"Eva","family":"Helaskoski","sequence":"first","affiliation":[{"name":"Occupational Medicine Finnish Institute of Occupational Health 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