{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:54:52Z","timestamp":1791212092823,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,11,13]],"date-time":"2014-11-13T00:00:00Z","timestamp":1415836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The International Fragrance Association (IFRA)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Oak moss absolute, an extract from the lichen <jats:italic>Evernia prunastri<\/jats:italic>, is a valued perfume ingredient but contains extreme allergens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the elicitation properties of two preparations of oak moss absolute: \u2018classic oak moss\u2019, the historically used preparation, and \u2018new oak moss\u2019, with reduced contents of the major allergens atranol and chloroatranol.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients\/materials\/methods<\/jats:title><jats:p>The two preparations were compared in randomized double\u2010blinded repeated open application tests and serial dilution patch tests in 30 oak moss\u2010sensitive volunteers and 30 non\u2010allergic control subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In both test models, new oak moss elicited significantly less allergic contact dermatitis in oak moss\u2010sensitive subjects than classic oak moss. The control subjects did not react to either of the preparations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>New oak moss is still a fragrance allergen, but elicits less allergic contact dermatitis in previously oak moss\u2010sensitized individuals, suggesting that new oak moss is less allergenic to non\u2010sensitized individuals.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12312","type":"journal-article","created":{"date-parts":[[2014,11,14]],"date-time":"2014-11-14T03:03:33Z","timestamp":1415934213000},"page":"75-83","source":"Crossref","is-referenced-by-count":23,"title":["Reduced content of chloroatranol and atranol in oak moss absolute significantly reduces the elicitation potential of this fragrance material"],"prefix":"10.1111","volume":"72","author":[{"given":"Flemming","family":"Andersen","sequence":"first","affiliation":[{"name":"Department of Dermatology and the Allergy Centre Odense University Hospital  Sdr. Boulevard 29 5000 Odense C Denmark"},{"name":"Dermatological Investigations Scandinavia  J. B. Winsl\u00f8wparken 9 5000 Odense C Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten H.","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and the Allergy Centre Odense University Hospital  Sdr. Boulevard 29 5000 Odense C Denmark"},{"name":"Dermatological Investigations Scandinavia  J. B. Winsl\u00f8wparken 9 5000 Odense C Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armand","family":"Bernois","sequence":"additional","affiliation":[{"name":"LVMH Recherche  Avenue de Verdun 185 45800 Saint Jean de Braye France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Brault","sequence":"additional","affiliation":[{"name":"LVMH Recherche  Avenue de Verdun 185 45800 Saint Jean de Braye France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Bruze","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University  S\u00f6dra F\u00f6rstadsgatan 101 214 28 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herv\u00e9","family":"Eudes","sequence":"additional","affiliation":[{"name":"Biolandes  Route de B\u00e9lis 40420 Le Sen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Gadras","sequence":"additional","affiliation":[{"name":"Robertet SA  Avenue Sidi Brahim 37 06130 Grasse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010C\u00e9cile J.","family":"Signoret","sequence":"additional","affiliation":[{"name":"Chanel SAS  Avenue Charles de Gaulle 135 92200 Neuilly\u2010sur\u2010Seine France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian F.","family":"Mose","sequence":"additional","affiliation":[{"name":"Department of Dermatology and the Allergy Centre Odense University Hospital  Sdr. Boulevard 29 5000 Odense C Denmark"},{"name":"Dermatological Investigations Scandinavia  J. B. Winsl\u00f8wparken 9 5000 Odense C Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris P.","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Symrise AG  M\u00fchlenfeldstra\u00dfe 1 37603 Holzminden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Toulemonde","sequence":"additional","affiliation":[{"name":"International Flavors &amp; Fragrances  Parc Industriel Les Bois de Grasse 06130 Grasse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus Ejner","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and the Allergy Centre Odense University Hospital  Sdr. Boulevard 29 5000 Odense C Denmark"},{"name":"Dermatological Investigations Scandinavia  J. B. Winsl\u00f8wparken 9 5000 Odense C Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ffj.1916"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-003-0426-3"},{"key":"e_1_2_7_4_1","unstructured":"SCCP.Opinion on Atranol and Chloroatranol present in natural extracts (e.g. oak moss and tree moss extract) SCCP\/00847\/04 2004. Available at:http:\/\/ec.europa.eu\/health\/ph_risk\/committees\/04_sccp\/docs\/sccp_o_006.pdf(last accessed 27 February 2014)."},{"key":"e_1_2_7_5_1","unstructured":"SCCP.Opinion on Oak moss\/Tree moss (sensitization only)SCCP\/1131\/07 2008. 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