{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:40:38Z","timestamp":1788871238628,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,11,19]],"date-time":"2014-11-19T00:00:00Z","timestamp":1416355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003035","name":"Aase og Ejnar Danielsens Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003035","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Aage Bang"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cobalt is a strong skin sensitizer and a prevalent contact allergen. Recent studies have recognized exposure to leather articles as a potential cause of cobalt allergy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine the association between contact allergy to cobalt and a history of dermatitis resulting from exposure to leather.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A questionnaire case\u2013control study was performed: the case group consisted of 183 dermatitis patients with a positive patch test reaction to cobalt chloride and a negative patch test reaction to potassium dichromate; the control group consisted of 621 dermatitis patients who did not react to either cobalt or chromium in patch testing. Comparisons were made by use of a \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u2010test, Fisher's exact, and the Mann\u2013Whitney test. Logistic regression analyses were used to test for associations while taking confounding factors into consideration.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Leather was observed as the most frequent exposure source causing dermatitis in the case group. Although the case group significantly more often reported non\u2010occupational dermatitis caused by leather exposure (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001), no association was found between cobalt allergy and dermatitis caused by work\u2010related exposure to leather.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study suggests a positive association between cobalt allergy and a history of dermatitis caused by non\u2010occupational exposure to leather articles.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cod.12319","type":"journal-article","created":{"date-parts":[[2014,11,19]],"date-time":"2014-11-19T05:47:43Z","timestamp":1416376063000},"page":"106-114","source":"Crossref","is-referenced-by-count":40,"title":["Association between cobalt allergy and dermatitis caused by leather articles \u2013 a questionnaire study"],"prefix":"10.1111","volume":"72","author":[{"given":"David","family":"Bregnbak","sequence":"first","affiliation":[{"name":"Department of Dermato\u2010Allergology National Allergy Research Centre, Copenhagen University Hospital Gentofte  Hellerup 2900, Niels Andersens Vej 65 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob P.","family":"Thyssen","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Allergology National Allergy Research Centre, Copenhagen University Hospital Gentofte  Hellerup 2900, Niels Andersens Vej 65 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"Zachariae","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Allergology Copenhagen University Hospital Gentofte  Hellerup 2900, Niels Andersens Vej 65 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torkil","family":"Menn\u00e9","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Allergology National Allergy Research Centre, Copenhagen University Hospital Gentofte  Hellerup 2900, Niels Andersens Vej 65 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne D.","family":"Johansen","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Allergology National Allergy Research Centre, Copenhagen University Hospital Gentofte  Hellerup 2900, Niels Andersens Vej 65 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