{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T18:46:12Z","timestamp":1780685172402,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,1,19]],"date-time":"2015-01-19T00:00:00Z","timestamp":1421625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Welander Foundation"},{"name":"\u00c3\u2013rebro County Council"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Contact allergy prevalence rates change over time as a result of variations in allergen exposure. Data from patch test clinics are often used as markers for allergy trends.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of the present retrospective study was to describe trends in rates of sensitization to allergens in the Swedish baseline series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients\/materials\/methods<\/jats:title><jats:p>Prevalence rates are described by comparing consecutive patch test data from 1992, 2000 and 2009 in Swedish patch test clinics. In total, 3680 patients were included in 1992, 3825 in 2000, and 3112 in 2009.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among test substances with a sensitization rate above 2% in 2009, significant decreases were noted for nickel sulfate, cobalt chloride, colophonium, and methylchloroisothiazolinone (<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>)\/methylisothiazolinone (<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content>), and a significant increase for <jats:italic>p<\/jats:italic>\u2010phenylenediamine, as compared with 1992. Potassium dichromate reactions had increased among younger women, whereas reactions to nickel and cobalt had decreased in this group. Sensitization to chromium, cobalt and fragrance mix I had decreased among older men, and sensitization to nickel had decreased among younger men.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>It is probable that these changes in 1992\u20132009 reflect both changes in regulations for nickel, lower levels of chromium in cement and of <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> in cosmetics, and increasing use of hair dyes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12346","type":"journal-article","created":{"date-parts":[[2015,1,20]],"date-time":"2015-01-20T02:14:12Z","timestamp":1421720052000},"page":"297-304","source":"Crossref","is-referenced-by-count":51,"title":["Contact allergy trends in Sweden \u2013 a retrospective comparison of patch test data from 1992, 2000, and 2009"],"prefix":"10.1111","volume":"72","author":[{"given":"Sofia","family":"Fall","sequence":"first","affiliation":[{"name":"Department of Dermatology \u00d6rebro University Hospital  SE\u2010701 82 \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Bruze","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University  SE\u2010205 02 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marl\u00e9ne","family":"Isaksson","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University  SE\u2010205 02 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carola","family":"Lid\u00e9n","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine, Karolinska Institutet  SE\u2010171 77 Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaly","family":"Matura","sequence":"additional","affiliation":[{"name":"Unit of Occupational and Environmental Dermatology Centre for Occupational and Environmental Medicine, SE\u2010113 65 Stockholm County Council  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berndt","family":"Stenberg","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology, Department of Public Health and Clinical Medicine Ume\u00e5 University  SE\u2010901 85 Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Lindberg","sequence":"additional","affiliation":[{"name":"Department of Dermatology \u00d6rebro University Hospital  SE\u2010701 82 \u00d6rebro Sweden"},{"name":"Department of Dermatology Faculty of Medicine and Health, \u00d6rebro University  SE\u2010701 82 \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2012.02834.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03362.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2006.01063.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-03827-3_24"},{"key":"e_1_2_6_6_1","first-page":"507","article-title":"The epidemiology of contact allergy. 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