{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:47:17Z","timestamp":1791388037836,"version":"4.3.3"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,2,18]],"date-time":"2015-02-18T00:00:00Z","timestamp":1424217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2015,6]]},"abstract":"Summary<\/jats:title>Background<\/jats:title>Chronic hand eczema is a common dermatological disorder of multifactorial aetiology. It affects physical, material, social and psychological aspects of life, thereby impairing health\u2010related quality of life.<\/jats:p><\/jats:sec>Objectives<\/jats:title>The aim of the present study was to assess quality of life, anxiety, depression and obsessive\u2010compulsive tendencies in patients with chronic hand eczema.<\/jats:p><\/jats:sec>Materials and methods<\/jats:title>Seventy\u2010one patients with chronic hand eczema were included in the study. Quality of life was evaluated according to the D<\/jats:styled-content>ermatology L<\/jats:styled-content>ife Q<\/jats:styled-content>uality I<\/jats:styled-content>ndex (DLQI<\/jats:styled-content>). Patients were also assessed for anxiety and depression with the H<\/jats:styled-content>ospital A<\/jats:styled-content>nxiety and D<\/jats:styled-content>epression S<\/jats:styled-content>cale (HADS<\/jats:styled-content>), and for compulsive behaviour with the L<\/jats:styled-content>eyton T<\/jats:styled-content>rait S<\/jats:styled-content>cale.<\/jats:p><\/jats:sec>Results<\/jats:title>The DLQI<\/jats:styled-content> score was 11.11\u2009\u00b1\u20091.81 in patients with chronic hand eczema. Scores on the L<\/jats:styled-content>eyton T<\/jats:styled-content>rait S<\/jats:styled-content>cale were significantly higher than those of healthy controls (p<\/jats:italic>\u2009<\u20090.027). As concerns the HADS<\/jats:styled-content>\u2010Anxiety subscale, patients with hand dermatitis had statistically significantly higher scores than those of volunteers (p<\/jats:italic>\u2009=\u20090.002). In contrast, no statistically significant difference was found between the two groups with regard to the HADS<\/jats:styled-content>\u2010Depression subscale score and total HADS<\/jats:styled-content> score.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Hand eczema treatment should address the severity of skin lesions as well as the psychological impact of hand eczema.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12366","type":"journal-article","created":{"date-parts":[[2015,2,19]],"date-time":"2015-02-19T02:16:48Z","timestamp":1424312208000},"page":"367-370","source":"Crossref","is-referenced-by-count":48,"title":["Quality of life, anxiety, depression and obsessive\u2010compulsive tendencies in patients with chronic hand eczema"],"prefix":"10.1111","volume":"72","author":[{"given":"Anargyros","family":"Kouris","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology \u2018Andreas Sygros\u2019 Hospital 16121 Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalliopi","family":"Armyra","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology \u2018Andreas Sygros\u2019 Hospital 16121 Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Christodoulou","sequence":"additional","affiliation":[{"name":"2nd Department of Psychiatry National and Kapodistrian University of Athens Medical School, Attikon General University Hospital 10121 Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandros","family":"Katoulis","sequence":"additional","affiliation":[{"name":"2nd Department of Dermatology and Venereology National and Kapodistrian University of Athens Medical School, Attikon General University Hospital 10121 Athens 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