{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:08:46Z","timestamp":1791090526437,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,2,25]],"date-time":"2015-02-25T00:00:00Z","timestamp":1424822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003128","name":"Finnish Work Environment Fund","doi-asserted-by":"crossref","award":["113061"],"award-info":[{"award-number":["113061"]}],"id":[{"id":"10.13039\/501100003128","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2015,6]]},"abstract":"Summary<\/jats:title>Background<\/jats:title>Diglycidyl ether of bisphenol A<\/jats:styled-content> resin (DGEBA\u2010R<\/jats:styled-content>) is the most common sensitizer in epoxy systems, but a minority of patients also develop contact allergy to reactive diluents.<\/jats:p><\/jats:sec>Objectives<\/jats:title>To analyse the frequency and clinical relevance of allergic reactions to different epoxy reactive diluents and related aliphatic epoxy resins.<\/jats:p><\/jats:sec>Methods<\/jats:title>Test files (J<\/jats:styled-content>anuary 1991 to J<\/jats:styled-content>une 2014) were screened, and the clinical records of patients with allergic reactions were analysed for occupation, concomitant allergic reactions, and exposure.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 67 patients reacted to at least one of the compounds. The largest numbers of allergic reactions were to phenyl glycidyl ether (PGE<\/jats:styled-content>; n\u2009=\u200941), 1,4\u2010butanediol diglycidyl ether (BDDGE<\/jats:styled-content>; n\u2009=\u200934), and p<\/jats:italic>\u2010tert\u2010butylphenyl glycidyl ether (PTBPGE<\/jats:styled-content>; n\u2009=\u200919). Ten of the patients did not have contact allergy to DGEBA\u2010R<\/jats:styled-content>. The reactions of 5 of these were related to the use of BDDGE<\/jats:styled-content>\u2010containing products. We found no significant exposure to PGE<\/jats:styled-content> or PTBPGE<\/jats:styled-content> in patients sensitized to them, but some of the patients had used cresyl glycidyl ether\u2010containing products.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Allergic reactions to reactive diluents and related aliphatic epoxy resins usually occurred together with reactions to DGEBA\u2010R<\/jats:styled-content>. BDDGE<\/jats:styled-content> was the clinically most significant compound, and was the sole cause of occupational allergic contact dermatitis in 3 patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12369","type":"journal-article","created":{"date-parts":[[2015,2,25]],"date-time":"2015-02-25T05:54:48Z","timestamp":1424843688000},"page":"387-397","source":"Crossref","is-referenced-by-count":30,"title":["Contact allergy to reactive diluents and related aliphatic epoxy resins"],"prefix":"10.1111","volume":"72","author":[{"given":"Kristiina","family":"Aalto\u2010Korte","sequence":"first","affiliation":[{"name":"Occupational Medicine Finnish Institute of Occupational Health (FIOH) 00250 Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Outi","family":"Kuuliala","sequence":"additional","affiliation":[{"name":"Occupational Medicine Finnish Institute of Occupational Health (FIOH) 00250 Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maj\u2010Len","family":"Henriks\u2010Eckerman","sequence":"additional","affiliation":[{"name":"Occupational Hygiene Finnish Institute of Occupational Health (FIOH) 20520 Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katri","family":"Suuronen","sequence":"additional","affiliation":[{"name":"Occupational Medicine Finnish Institute of Occupational Health (FIOH) 00250 Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,25]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Ullmann's Encyclopedia of Industrial Chemistry","author":"Pham H Q","year":"2005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.44020920.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2004.20433"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-74299-6_75"},{"key":"e_1_2_6_6_1","first-page":"1","article-title":"Occupational skin diseases from epoxy compounds. 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