{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T07:16:58Z","timestamp":1769843818031,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,3,20]],"date-time":"2015-03-20T00:00:00Z","timestamp":1426809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2015,8]]},"abstract":"Summary<\/jats:title>Background<\/jats:title>Primin is the main contact allergen found in the ornamental plant Primula obconica<\/jats:italic> H<\/jats:styled-content>ance.<\/jats:p><\/jats:sec>Objective<\/jats:title>To analyse the temporal trend of sensitivity to primin in north\u2010eastern Italy and to evaluate the associations with occupations in our geographical area.<\/jats:p><\/jats:sec>Methodology<\/jats:title>From 1996 to 2012, 24\u2009052 consecutive patients with suspected allergic contact dermatitis were patch tested in north\u2010eastern I<\/jats:styled-content>taly. Individual characteristics were collected through a standardized questionnaire in eight departments of dermatology or occupational medicine.<\/jats:p><\/jats:sec>Results<\/jats:title>The overall prevalence of primin sensitization was 1.9%; the prevalence was significantly higher in women (2.6%) than in men (0.5%). The Pordenone area had the higher prevalence of sensitization, which reached 6% in 1999\u20132001. We found a significant association between primin sensitization and household workers [odds ratio (OR<\/jats:styled-content>) 2.3; 95% confidence interval (CI<\/jats:styled-content>): 1.61\u20133.35], retired people (OR<\/jats:styled-content> 1.8; 95%CI<\/jats:styled-content>: 1.22\u20132.81), woodworkers (OR<\/jats:styled-content> 2.1; 95%CI<\/jats:styled-content>: 1.10\u20136.18), and chemical industry workers (OR<\/jats:styled-content> 2.9; 95%CI<\/jats:styled-content>: 1.05\u20138.29).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Our study showed that contact allergy to primin is still relevant in north\u2010eastern I<\/jats:styled-content>taly. The frequency of sensitization is decreasing, but for retired and household workers it is still >4%. Our results suggest the need to promote the use of primin\u2010free P. obconica<\/jats:italic> in I<\/jats:styled-content>taly.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12385","type":"journal-article","created":{"date-parts":[[2015,3,20]],"date-time":"2015-03-20T22:20:23Z","timestamp":1426890023000},"page":"108-112","source":"Crossref","is-referenced-by-count":15,"title":["Primin sensitization in north\u2010eastern I<\/scp>taly: a temporal trend from 1996 to 2012"],"prefix":"10.1111","volume":"73","author":[{"given":"Lorenzo","family":"Bongiorni","sequence":"first","affiliation":[{"name":"Clinical Unit of Occupational Medicine University of Trieste Trieste 34129 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Prodi","sequence":"additional","affiliation":[{"name":"Clinical Unit of Occupational Medicine University of Trieste Trieste 34129 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Rui","sequence":"additional","affiliation":[{"name":"Clinical Unit of Occupational Medicine University of Trieste Trieste 34129 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Belloni Fortina","sequence":"additional","affiliation":[{"name":"Sezione di Dermatologia Pediatrica, Dipartimento di Salute della Donna e del Bambino University of Padova Padova 35100 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria T.","family":"Corradin","sequence":"additional","affiliation":[{"name":"Divisione di Dermatologia Ospedale Santa Maria degli Angeli Pordenone 33170 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Larese Filon","sequence":"additional","affiliation":[{"name":"Clinical Unit of Occupational Medicine University of Trieste Trieste 34129 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