{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:49:33Z","timestamp":1782125373895,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,4,23]],"date-time":"2015-04-23T00:00:00Z","timestamp":1429747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Mekos Laboratories A\/S"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In a population study using <jats:styled-content style=\"fixed-case\">TRUE Test\u00ae<\/jats:styled-content>, we noted late reactions to <jats:styled-content style=\"fixed-case\"><jats:italic>p\u2010tert<\/jats:italic><\/jats:styled-content>\u2010butylphenol\u2010formaldehyde resin (<jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content>) in 0.5% of subjects tested.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>In order to explore possible test sensitization, differences in the contents of sensitizers within <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> in test preparations for <jats:styled-content style=\"fixed-case\">TRUE Test\u00ae<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">Finn Chambers\u00ae<\/jats:styled-content> were analysed. Subjects allergic to <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> and subjects with late reactions to <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> were retested in order to explore whether these groups reacted to different <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> sensitizers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients\/materials\/methods<\/jats:title><jats:p>Four individuals with late reactions and 5 subjects with established allergy to <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> were retested with defined <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> sensitizers. <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> constituents in patches from <jats:styled-content style=\"fixed-case\">TRUE Test\u00ae<\/jats:styled-content> were analysed with high\u2010performance liquid chromatography. Previously analysed samples of <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> constituents served as a reference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The pattern of reaction to <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> sensitizers was similar in both groups. Subjects with suspected sensitization had somewhat stronger reactions than controls. The concentrations of monomers, dimers and trimers were generally higher in the <jats:styled-content style=\"fixed-case\">TRUE Test\u00ae<\/jats:styled-content> resin than in reference substances.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Retesting did not add information regarding causes of possible sensitization. Analysis showed that the resin used in <jats:styled-content style=\"fixed-case\">TRUE Test\u00ae<\/jats:styled-content> has a lower degree of polymerization or condensation, which may enhance its sensitizing properties. A follow\u2010up of late reactions to <jats:styled-content style=\"fixed-case\">PTBP\u2010FR<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">TRUE Test\u00ae<\/jats:styled-content> should be carried out.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12401","type":"journal-article","created":{"date-parts":[[2015,4,23]],"date-time":"2015-04-23T06:31:24Z","timestamp":1429770684000},"page":"350-357","source":"Crossref","is-referenced-by-count":9,"title":["Is <i>p\u2010tert<\/i>\u2010butylphenol\u2010formaldehyde resin (<scp>PTBP\u2010FR<\/scp>) in <scp>TRUE T<\/scp>est\u00ae (<scp>M<\/scp>ekos test) sensitizing the tested patients?"],"prefix":"10.1111","volume":"73","author":[{"given":"Berndt","family":"Stenberg","sequence":"first","affiliation":[{"name":"Department of Public Health and Clinical Medicine, Dermatology and Venereology Ume\u00e5 University  901 85 Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Bruze","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University  214 28 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Zimerson","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital, Lund University  214 28 Malm\u00f6 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