{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T10:40:32Z","timestamp":1784198432735,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,9,14]],"date-time":"2015-09-14T00:00:00Z","timestamp":1442188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Wet work tasks are the most common exposures leading to occupational irritant contact dermatitis. Use of liquid\u2010proof gloves is recommended when performing wet work, however, gloves may also contribute to impairment of the skin barrier and development of irritant contact dermatitis. The aim of this study is to review the literature on the effects of glove occlusion on skin barrier function. The <jats:styled-content style=\"fixed-case\">PubMed<\/jats:styled-content> database was searched up to 1 February 2015 for articles on the association between glove occlusion and skin barrier function, including human studies only and in English. Only experimental studies including assessment of the skin barrier function were included in the data analysis. Thirteen articles were identified, 8 with focus on occlusion alone, 7 with focus on occlusion in combination with irritant exposure (some overlapping), and 2 field studies. In conclusion, data from the literature showed that the negative effect of occlusion in itself is limited, and that only extensive and long\u2010term occlusion will cause barrier impairment. However, studies investigating combined effect of occlusion and exposure to soaps\/detergents indicate that occlusion significantly enhances the skin barrier damage caused by detergents\/soaps in a dose\u2010response fashion.<\/jats:p>","DOI":"10.1111\/cod.12470","type":"journal-article","created":{"date-parts":[[2015,9,14]],"date-time":"2015-09-14T07:21:22Z","timestamp":1442215282000},"page":"2-10","source":"Crossref","is-referenced-by-count":74,"title":["Effect of glove occlusion on the skin barrier"],"prefix":"10.1111","volume":"74","author":[{"given":"Daniel","family":"Tiedemann","sequence":"first","affiliation":[{"name":"Department of Dermatology Bispebjerg Hospital, University of Copenhagen  2400 Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja Lisa","family":"Clausen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bispebjerg Hospital, University of Copenhagen  2400 Copenhagen 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