{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:57:59Z","timestamp":1783025879569,"version":"3.54.6"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,25]],"date-time":"2016-01-25T00:00:00Z","timestamp":1453680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2016,4]]},"abstract":"Summary<\/jats:title>Background<\/jats:title>Essential oils are fragrance substances that are labelled on cosmetic products by their INCI names, potentially confusing consumers.<\/jats:p><\/jats:sec>Objectives<\/jats:title>To establish whether contact allergy to essential oils might be missed if not specifically tested for.<\/jats:p><\/jats:sec>Methods<\/jats:title>We tested 471 patients with 14 essential oils and 2104 patients with Melaleuca alternifolia<\/jats:italic> oil between January 2008 and June 2014. All patients were tested with fragrance mix I, fragrance mix II, hydroxyisohexyl 3\u2010cyclohexene carboxaldehyde, and Myroxylon pereirae<\/jats:italic>. Three hundred and twenty\u2010six patients were tested with hydroperoxides of limonene and linalool.<\/jats:p><\/jats:sec>Results<\/jats:title>Thirty\u2010four patients had a +\/++\/+++ reaction to at least one essential oil. Eleven had no reaction to any of the six marker fragrance substances. Thus, 4 of 11 positive reactions to M. alternifolia<\/jats:italic> oil, 2 of 7 reactions to Cymbopogon flexuosus<\/jats:italic> oil, 1 of 5 reactions to Cananga odorata<\/jats:italic> oil, 3 of 4 reactions to Santalum album<\/jats:italic> oil and 2 of 3 reactions to Mentha piperita<\/jats:italic> oil would have been missed without individual testing.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>A small number of patients who are allergic to essential oils could be missed if these are not specifically tested. Labelling by INCI names means that exposure may not be obvious. Careful inspection of so\u2010called \u2018natural\u2019 products and targeted testing is recommended.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12528","type":"journal-article","created":{"date-parts":[[2016,1,25]],"date-time":"2016-01-25T08:03:38Z","timestamp":1453709018000},"page":"236-241","source":"Crossref","is-referenced-by-count":27,"title":["Contact allergy to essential oils cannot always be predicted from allergy to fragrance markers in the baseline series"],"prefix":"10.1111","volume":"74","author":[{"given":"Ruth A.","family":"Sabroe","sequence":"first","affiliation":[{"name":"Department of Dermatology Sheffield Teaching Hospitals NHS Foundation Trust Sheffield S10 2JF UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine R.","family":"Holden","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sheffield Teaching Hospitals NHS Foundation Trust Sheffield S10 2JF UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Gawkrodger","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sheffield Teaching Hospitals NHS Foundation Trust Sheffield S10 2JF UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09157.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12117"},{"key":"e_1_2_5_4_1","unstructured":"EU Scientific Committee on Cosmetic and Non\u2010Food Products Intended for Consumers.Fragrance Allergy in Consumers. A review of the problem. Brussels EU Commission DG SANCO SCCNFP\/0017\/98 final 18th December1999."},{"key":"e_1_2_5_5_1","volume-title":"Essential Oil Safety: A Guide for Health Care Professionals","author":"Tisserand R","year":"2013"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01402.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2010.01768.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12420"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.0350f.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2007.00341.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12293"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2004.04034"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12199"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.6802"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12171"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13037"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12528","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.12528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T16:25:41Z","timestamp":1696350341000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.12528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,25]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1111\/cod.12528"],"URL":"https:\/\/doi.org\/10.1111\/cod.12528","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,25]]}}}