{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:21:21Z","timestamp":1790396481248,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T00:00:00Z","timestamp":1464048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The individual burden of disease in hand eczema patients is considerable. However, little is known about the socio\u2010economic impact of this disease. The aims of this review were to evaluate the literature on cost\u2010of\u2010illness in hand eczema, and to compose a checklist for future use. The literature was retrieved from the <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">EMBASE<\/jats:styled-content> databases up to <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ctober 2015. Quality evaluation was based on seven relevant items in cost\u2010of\u2010illness studies. Cost data (direct and indirect) were extracted and converted into euros (2014 price level) by use of the <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>utch <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>onsumer <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>rice <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex. Six articles were included. The mean annual total cost per patient ranged from \u20ac1712 to \u20ac9792 (direct cost per patient, \u20ac521 to \u20ac3829; and indirect cost per patient, \u20ac100 to \u20ac6846). Occupational hand eczema patients showed indirect costs up to 70% of total costs, mainly because of absenteeism. A large diversity in hand eczema severity was found between studies. The socio\u2010economic burden of hand eczema is considerable, especially for more severe and\/or occupational hand eczema. Absenteeism from paid work leads to a high total cost\u2010of\u2010illness, although disregard of presenteeism often leads to underestimation of indirect costs. Differences in included cost components, the occupational status of patients and hand eczema severity make international comparison difficult. A checklist was added to standardize the approach to cost\u2010of\u2010illness studies in hand eczema.<\/jats:p>","DOI":"10.1111\/cod.12590","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T20:21:47Z","timestamp":1464121307000},"page":"67-76","source":"Crossref","is-referenced-by-count":65,"title":["Systematic review of cost\u2010of\u2010illness studies in hand eczema"],"prefix":"10.1111","volume":"75","author":[{"given":"Klaziena","family":"Politiek","sequence":"first","affiliation":[{"name":"Department of Dermatology University Medical Centre Groningen, University of Groningen  9700 RB Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jart A. F.","family":"Oosterhaven","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Centre Groningen, University of Groningen  9700 RB Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin M.","family":"Vermeulen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University Medical Centre Groningen, University of Groningen  9700 RB Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Louise A.","family":"Schuttelaar","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Centre Groningen, University of Groningen  9700 RB Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2009.01669.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1104084"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09099.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13371"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09987.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2012.02062.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000100"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2165\/11588380-000000000-00000"},{"key":"e_1_2_6_10_1","volume-title":"Handleiding voor kostenonderzoek, methoden en standaard kostprijzen voor economische evaluaties in de gezondheidszorg","author":"Hakkaart\u2010van Roijen L","year":"2010"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-015-0325-4"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-0172(97)80044-3"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20410"},{"key":"e_1_2_6_14_1","first-page":"41","volume-title":"Methods for the Economic Evaluation of Health Care Programmes","author":"Drummond M F","year":"2015"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12130"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10427.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12038"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1565"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.11.1053"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12095"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12510_1"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.jom.0000166864.58664.29"},{"key":"e_1_2_6_23_1","first-page":"e171","article-title":"A systematic review of measurement properties of instruments assessing presenteeism","volume":"21","author":"Ospina M B","year":"2015","journal-title":"Am J Manag Care"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2015.05.009"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9960-1"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-013-0056-3"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08487.x"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12590","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12590","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.12590","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:21:49Z","timestamp":1695572509000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.12590"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,24]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1111\/cod.12590"],"URL":"https:\/\/doi.org\/10.1111\/cod.12590","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,24]]}}}