{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:40:58Z","timestamp":1787244058769,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T00:00:00Z","timestamp":1467158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      A tertiary individual prevention programme (\n                      <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                      ) is offered to patients with severe occupational skin disease (\n                      <jats:styled-content style=\"fixed-case\">OSD<\/jats:styled-content>\n                      ) in Germany. Previously, it was shown that the burden of\n                      <jats:styled-content style=\"fixed-case\">OSD<\/jats:styled-content>\n                      s is considerably reduced in patients up to 1 year after the\n                      <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To evaluate the long\u2010term effects of the\n                      <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>\n                      In a prospective multicentre cohort study, the clinical and patient\u2010reported outcome data 3 years after the\n                      <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                      were evaluated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 1788 patients initially included in the study, 1410 were available for the 3\u2010year follow\u2010up analysis. The severity of\n                      <jats:styled-content style=\"fixed-case\">OSD<\/jats:styled-content>\n                      , the use of topical corticosteroids and days of absence from work were significantly reduced 3 years after the\n                      <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                      , and the quality of life and skin protective behaviour were significantly improved. Of the patients, 96.9% were able to resume work. One thousand one hundred and sixty\n                      <jats:italic>\u2010<\/jats:italic>\n                      six patients (82.7%) were still working 3 years after the\n                      <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                      , 874 of them (75.0%) in the same occupational field. Hairdressers had the lowest rate of remaining in their original profession (41.3%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The follow\u2010up during 3 years of this unique cohort of patients with\n                      <jats:styled-content style=\"fixed-case\">OSD<\/jats:styled-content>\n                      s shows that the\n                      <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                      is associated with sustained improvements in terms of disease severity, ability to work, quality of life, and prognosis.\n                    <\/jats:p>\n                  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69115 Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Ofenloch","sequence":"additional","affiliation":[{"name":"Department of Clinical Social Medicine, Occupational and Environmental Dermatology University of Heidelberg  69115 Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Elsner","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Jena  07743 Jena Germany"},{"name":"Statutory Accident Insurance Clinic of Occupational Diseases  08233 Falkenstein Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britta","family":"Wulfhorst","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck  49090 Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) at the University of Osnabr\u00fcck and Dermatologic Centre Trauma Hospital  21033 Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sch\u00f6nfeld","sequence":"additional","affiliation":[{"name":"Clinic for Occupational Diseases of the VBG (Statutory Accident Insurance)  83435 Bad Reichenhall Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swen M.","family":"John","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck  49090 Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) at the University of Osnabr\u00fcck and Dermatologic Centre Trauma Hospital  21033 Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas L.","family":"Diepgen","sequence":"additional","affiliation":[{"name":"Department of Clinical Social Medicine, Occupational and 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