{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:13:12Z","timestamp":1780319592928,"version":"3.54.1"},"reference-count":53,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T00:00:00Z","timestamp":1489622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007273","name":"Comisi\u00f3n Interministerial de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["CTQ 2013\u201044998\u2010P"],"award-info":[{"award-number":["CTQ 2013\u201044998\u2010P"]}],"id":[{"id":"10.13039\/501100007273","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Many skin diseases are associated with either increases or decreases in lamellar body secretion, or dysfunctional lamellar bodies. Consequently, diseased skin is characterized by reduced barrier function and altered lipid composition and organization. Human skin is commonly evaluated <jats:italic>in\u2009vivo<\/jats:italic> with non\u2010invasive biophysical techniques. The dynamic functions of the skin are evaluated with repeat measurements such as the sorption\u2013desorption test (<jats:styled-content style=\"fixed-case\">SDT<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to evaluate <jats:italic>in\u2009vivo<\/jats:italic> skin hydration\u2013dehydration kinetics after treatment with a lipid system that mimics the morphology, structure and composition of lamellar bodies in both healthy and irritated human skin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A patch with an aqueous solution of 2% sodium lauryl sulfate (<jats:styled-content style=\"fixed-case\">SLS<\/jats:styled-content>) was used to irritate the skin of the volunteers. The <jats:styled-content style=\"fixed-case\">SDT<\/jats:styled-content> was performed with the <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> 820 corneometer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After treatment with this system, both healthy and <jats:styled-content style=\"fixed-case\">SLS<\/jats:styled-content>\u2010irritated skin increased their ability to retain water and to release water slowly during the desorption phase.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Treatment with this system seems to reinforce the barrier function in both healthy and <jats:styled-content style=\"fixed-case\">SLS<\/jats:styled-content>\u2010irritated human skin. Therefore, the present study provides evidence that this system could be of interest for developing future treatments for protecting and repairing the skin.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12771","type":"journal-article","created":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T17:35:52Z","timestamp":1489685752000},"page":"25-34","source":"Crossref","is-referenced-by-count":4,"title":["Sorption\u2013desorption test for functional assessment of skin treated with a lipid system that mimics epidermal lamellar bodies"],"prefix":"10.1111","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1246-5713","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"Moner","sequence":"first","affiliation":[{"name":"Department of Chemical and Surfactant Technology Institute of Advanced Chemistry of Catalonia (IQAC\u2010CSIC)  08034 Barcelona 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