{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:08:34Z","timestamp":1790089714561,"version":"4.0.1"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T00:00:00Z","timestamp":1502668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2017,12]]},"abstract":"SUMMARY<\/jats:title>\n \n Background<\/jats:title>\n \n Glucose sensors, such as\n F<\/jats:styled-content>\n ree\n S<\/jats:styled-content>\n tyle\u00ae\n L<\/jats:styled-content>\n ibre, are innovative medical devices developed for diabetes patients as a replacement for classic glucose meters, ensuring continuous glucose monitoring without the disadvantage of regular skin finger pricks.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n To report several cases of allergic contact dermatitis caused by\n F<\/jats:styled-content>\n ree\n S<\/jats:styled-content>\n tyle\u00ae\n L<\/jats:styled-content>\n ibre, and to report on isobornyl acrylate as a culprit allergen.\n <\/jats:p>\n <\/jats:sec>\n \n \n Patients and\n M<\/jats:styled-content>\n ethods\n <\/jats:title>\n \n Fifteen patients presented with allergic contact dermatitis caused by\n F<\/jats:styled-content>\n ree\n S<\/jats:styled-content>\n tyle\u00ae\n L<\/jats:styled-content>\n ibre. All but 1 were patch tested with a baseline series, and with pieces and\/or ultrasonic bath extracts of (the adhesive part of) the glucose sensor. Isobornyl acrylate was patch tested, in various concentrations and vehicles, in 13 patients. Gas chromatography\u2013mass spectrometry (\n GC<\/jats:styled-content>\n \u2010\n MS<\/jats:styled-content>\n ) of the sensors was performed.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n All patients reacted to the adhesive part of the sensor, and 12 patients were shown to be sensitized to isobornyl acrylate. Simultaneous reactions to other allergens were rarely observed.\n GC\u2010MS<\/jats:styled-content>\n showed the presence of isobornyl acrylate in the sensors.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Cases of allergic contact dermatitis caused by\n F<\/jats:styled-content>\n ree\n S<\/jats:styled-content>\n tyle\u00ae\n L<\/jats:styled-content>\n ibre are increasingly being observed, and isobornyl acrylate is a relevant culprit allergen. Cross\u2010reactivity to other acrylates was infrequently observed, but other, hitherto unidentified, contact allergens may still be present in the device.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/cod.12866","type":"journal-article","created":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T01:42:37Z","timestamp":1502674957000},"page":"367-373","source":"Crossref","is-referenced-by-count":182,"title":["Allergic contact dermatitis caused by isobornyl acrylate in\n F<\/scp>\n reestyle\u00ae\n L<\/scp>\n ibre, a newly introduced glucose sensor"],"prefix":"10.1111","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7000-1672","authenticated-orcid":false,"given":"Anne","family":"Herman","sequence":"first","affiliation":[{"name":"Department of Dermatology Cliniques Universitaires Saint\u2010Luc 1200 Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0076-2887","authenticated-orcid":false,"given":"Olivier","family":"Aerts","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Antwerp and University of Antwerp 2650 Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Baeck","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cliniques Universitaires Saint\u2010Luc 1200 Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2919-3227","authenticated-orcid":false,"given":"Magnus","family":"Bruze","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital 205 02 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"De Block","sequence":"additional","affiliation":[{"name":"Department of Endocrinology\u2010Diabetology\u2010Metabolism University Hospital Antwerp (UZA) and University of Antwerp (UA) 2650 Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9805-3439","authenticated-orcid":false,"given":"An","family":"Goossens","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospitals, KU Leuven 3000 Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Hamnerius","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital 205 02 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Huygens","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospitals, KU Leuven 3000 Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Maiter","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Cliniques Universitaires Saint\u2010Luc 1200 Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Tennstedt","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cliniques Universitaires Saint\u2010Luc 1200 Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Vandeleene","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Cliniques Universitaires Saint\u2010Luc 1200 Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6172-9274","authenticated-orcid":false,"given":"Martin","family":"Mowitz","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital 205 02 Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01634989-199209000-00004"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1995.tb00554.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.5507\/bp.2007.044"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12503"},{"key":"e_1_2_6_7_1","first-page":"115","article-title":"Isobornyl acrylate: an impurity in alkyl glucosides","volume":"35","author":"Foti C","year":"2016","journal-title":"Cutan Ocul 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Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12866","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.12866","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T08:00:11Z","timestamp":1696665611000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.12866"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,14]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/cod.12866"],"URL":"https:\/\/doi.org\/10.1111\/cod.12866","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,14]]}}}