{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:46:17Z","timestamp":1790520377118,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,9,21]],"date-time":"2017-09-21T00:00:00Z","timestamp":1505952000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the temporal development of lanolin allergy (i.e. positive reaction to lanolin alcohols and\/or <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>merchol\u2122 <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2010101), and the association between contact allergy to lanolin and patient characteristics from the <jats:styled-content style=\"fixed-case\">MOAHLFA<\/jats:styled-content> index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective observational study of consecutively patch tested dermatitis patients (n\u2009=\u20099577) between 1 January 2004 and 31 December 2015 with lanolin alcohols 30% pet. and <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>merchol\u2122 <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2010101 50% pet. was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of lanolin allergy increased from 0.45% in 2004 to 1.81% in 2015. In age\u2010adjusted and sex\u2010adjusted analyses, weak, significant associations were found between atopic dermatitis and lanolin and lanolin alcohols allergy, respectively, but no association with <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>merchol\u2122 <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2010101 allergy was found. Among 9286 dermatitis patients who were tested with both allergens, 108 had a positive test reaction to either lanolin alcohols or <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>merchol\u2122 <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2010101, whereas only 29 patients had positive test reactions to both markers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prevalence of lanolin contact allergy has increased over a 12\u2010year period, and inclusion of <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>merchol\u2122 <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2010101 will increase the chance of detecting lanolin contact allergy. Patch testing with lanolin is helpful in atopics with dermatitis and suspected cosmetic allergy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12872","type":"journal-article","created":{"date-parts":[[2017,9,22]],"date-time":"2017-09-22T04:16:47Z","timestamp":1506053807000},"page":"70-75","source":"Crossref","is-referenced-by-count":44,"title":["Contact allergy to lanolin: temporal changes in prevalence and association with atopic dermatitis"],"prefix":"10.1111","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6876-1100","authenticated-orcid":false,"given":"Marloes","family":"Fransen","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital University of Copenhagen  2900 Hellerup Denmark"},{"name":"Department of Dermatology Maastricht University Medical Centre  P.O. Box 5800, 6202 AZ Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line E. K.","family":"Overgaard","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital University of Copenhagen  2900 Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne D.","family":"Johansen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital University of Copenhagen  2900 Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob P.","family":"Thyssen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital University of Copenhagen  2900 Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1997.tb00398.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1998.tb05856.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1984.tb00054.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1981.tb03984.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e3182937aa4"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.00541.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2009.08081"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12358"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15065"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12229"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2012.02863.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04277.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2003.0227.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000097"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.00673.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.4064"},{"key":"e_1_2_6_19_1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jaad.2010.07.047","article-title":"The lanolin paradox revisited","volume":"64","author":"Matiz C","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12750"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000063356"},{"key":"e_1_2_6_22_1","first-page":"1","article-title":"The current spectrum of contact sensitization in patients with chronic leg ulcers or stasis dermatitis\u00a0\u2013\u00a0new data from the Information Network of Departments of Dermatology (IVDK)","volume":"76","author":"Erfurt\u2010Berge C","year":"2017","journal-title":"Contact Dermatitis"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01220.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12711"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2003.00033.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06465.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01155.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2003.480209.x"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12872","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.12872","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T23:46:49Z","timestamp":1696031209000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.12872"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,21]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1111\/cod.12872"],"URL":"https:\/\/doi.org\/10.1111\/cod.12872","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,21]]}}}