{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T18:50:22Z","timestamp":1771872622050,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,27]],"date-time":"2017-10-27T00:00:00Z","timestamp":1509062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Health and Safety Executive in the United Kingdom","award":["PRJ500"],"award-info":[{"award-number":["PRJ500"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Fragrances are well known to cause allergic contact dermatitis (ACD). Occupationally related cases occur, with certain groups being at higher risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the incidence of occupationally related cases of cutaneous fragrance allergy and to evaluate trends.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Data on incident cases of occupational ACD caused by fragrances between 1996 and 2015 (inclusive) reported to the EPIDERM surveillance scheme were analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the cases reported to EPIDERM during the study period, 5.2% had ACD attributed to fragrances. The highest annual incidence rates were observed in women. Hairdressers, beauticians and people working in related occupations had a 47\u2010fold higher incidence rate ratio than the reference category (the average of all other occupations combined). Trends analysis suggested a non\u2010significant increase in fragrance allergy over the study period among all occupations, and beauty and food workers, and a slight decrease in healthcare workers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Fragrance allergy is a significant problem in an occupational setting. Although there was no significant change in the incidence of fragrance\u2010related allergic occupational contact dermatitis (OCD) during the 20\u2010year study period, this does not mirror the trend in OCD, which is falling. Fragrance allergy continues to be a major contributor to OCD, and contributes to a greater proportion of cases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12902","type":"journal-article","created":{"date-parts":[[2017,10,27]],"date-time":"2017-10-27T10:42:01Z","timestamp":1509100921000},"page":"33-40","source":"Crossref","is-referenced-by-count":30,"title":["UK trends of allergic occupational skin disease attributed to fragrances 1996\u20132015"],"prefix":"10.1111","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6657-9145","authenticated-orcid":false,"given":"Rachel L.","family":"Montgomery","sequence":"first","affiliation":[{"name":"Leeds Teaching Hospitals NHS Trust \u2013 Centre for Dermatology Chapel Allerton Hospital  Leeds LS7 4SA UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond","family":"Agius","sequence":"additional","affiliation":[{"name":"Centre for Occupational and Environmental Health University of Manchester  Manchester M13 9PL UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7253-3461","authenticated-orcid":false,"given":"Stephen M.","family":"Wilkinson","sequence":"additional","affiliation":[{"name":"Leeds Teaching Hospitals NHS Trust \u2013 Centre for Dermatology Chapel Allerton Hospital  Leeds LS7 4SA UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Carder","sequence":"additional","affiliation":[{"name":"Centre for Occupational and Environmental Health University of Manchester  Manchester M13 9PL UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14167"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.450406.x"},{"key":"e_1_2_7_4_1","unstructured":"The Health and Occupation Research Network. 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