{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:20Z","timestamp":1787014040064,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T00:00:00Z","timestamp":1515628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Risk factors for\n                      <jats:italic>p<\/jats:italic>\n                      \u2010phenylenediamine (PPD) sensitization include the use of hair dyes, the application of temporary black henna tattoos, working as a hairdresser, and, possibly, exposure to hair dye pretests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To quantify the impact of these (putative) risk factors on PPD sensitization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Six items related to PPD exposure were added to the routine Information Network of Departments of Dermatology questionnaire from 2008 to 2013. A retrospective analysis of data from 4314 patients tested with PPD 1% pet. was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the PPD\u2010positive patients (n\u2009=\u2009271), 80% had their hair dyed, and, of these, 57% subsequently developed scalp dermatitis, whereas only 11% had had a henna tattoo. The self\u2010administrated pretest with hair dye was performed by only a few patients, precluding a more detailed analysis. Hair dyeing [odds ratio (OR) 6.0; 95% confidence interval (CI): 3.9\u20139.4], henna tattoos (OR 2.4; 95%CI: 1.5\u20133.7) and being a hairdresser (OR 2.1; 95%CI: 1.3\u20133.2) increased the risk of PPD sensitization. Neither dyeing of own hair nor application of a temporary henna tattoo seemed to affect PPD sensitization in hairdressers.\n                      <jats:italic>p<\/jats:italic>\n                      \u2010Aminoaryl compounds more often gave positive reactions in patients with henna tattoo.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hair dyeing is the major risk factor for PPD sensitization in this clinical setting, and application of a temporary black henna tattoo may also lead to (strong) PPD sensitization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cod.12920","type":"journal-article","created":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T00:43:26Z","timestamp":1515631406000},"page":"199-207","source":"Crossref","is-referenced-by-count":32,"title":["Factors associated with\n                    <i>p<\/i>\n                    \u2010phenylenediamine sensitization: data from the  Information Network of Departments of Dermatology,  2008\u20132013"],"prefix":"10.1111","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2359-2518","authenticated-orcid":false,"given":"Steffen","family":"Schubert","sequence":"first","affiliation":[{"name":"Information Network of Departments of Dermatology (IVDK) University of G\u00f6ttingen  37075 G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Lessmann","sequence":"additional","affiliation":[{"name":"Information Network of Departments of Dermatology (IVDK) University of G\u00f6ttingen  37075 G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Schnuch","sequence":"additional","affiliation":[{"name":"Information Network of Departments of Dermatology (IVDK) University of G\u00f6ttingen  37075 G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4498-3710","authenticated-orcid":false,"given":"Wolfgang","family":"Uter","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Biometry and Epidemiology Friedrich\u2010Alexander University Erlangen\u2010N\u00fcrnberg  91054 Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5047-8948","authenticated-orcid":false,"given":"Johannes","family":"Geier","sequence":"additional","affiliation":[{"name":"Information Network of Departments of Dermatology (IVDK) University of G\u00f6ttingen  37075 G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the IVDK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01427.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08644.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2015.10.064"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12074"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e318273a3b8"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01992.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2007.12.011"},{"key":"e_1_2_6_9_1","unstructured":"The Commission of the European Communities. Regulation (EC) No. 1223\/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products. Official Journal of the European Union 2009. Available at:https:\/\/ec.europa.eu\/health\/sites\/health\/files\/endocrine_disruptors\/docs\/cosmetic_1223_2009_regulation_en.pdf."},{"key":"e_1_2_6_10_1","first-page":"700","article-title":"Routine preliminary testing of products with oxidative hair colors before hair coloring presents problems and is refused. Position of the leadership of the German contact allergy group","volume":"3","author":"Schnuch A","year":"2005","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2012.02095.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2012.02078.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2012.02834.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.00406.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.5414\/DBP53107"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2009.06787.x"},{"key":"e_1_2_6_17_1","unstructured":"European Commission. SCCP (Scientific Committee on Consumer Products). Opinion on sensitivity to hair dyes\u00a0\u2013\u00a0consumer self testing 2007. 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